Screening for lung cancer with low-dose computed tomography: a review of current status

被引：64
作者：
Marshall, Henry M. [1 ,2 ]
Bowman, Rayleen V. [1 ,2 ]
Yang, Ian A. [1 ,2 ]
Fong, Kwun M. [1 ,2 ]
Berg, Christine D. [2 ,3 ]
机构：
[1] Prince Charles Hosp, Dept Thorac Med, Brisbane, Qld 4032, Australia
[2] Univ Queensland, Sch Med, Thorac Res Ctr, Brisbane, Qld, Australia
[3] NCI, Canc Prevent Div, Bethesda, MD 20892 USA
来源：
JOURNAL OF THORACIC DISEASE | 2013年 / 5卷
基金：
英国医学研究理事会;
关键词：
Lung neoplasms/mortality; mass screening tomography; helical computed; early detection of cancer/methods; SMALL PULMONARY NODULES; MAXIMUM INTENSITY PROJECTION; TERM-FOLLOW-UP; RISK PREDICTION; RANDOMIZED FEASIBILITY; MORTALITY REDUCTION; FLEISCHNER-SOCIETY; SELECTION CRITERIA; COST-EFFECTIVENESS; SMOKING-CESSATION;
D O I：
10.3978/j.issn.2072-1439.2013.09.06
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Screening using low-dose computed tomography (CT) represents an exciting new development in the struggle to improve outcomes for people with lung cancer. Randomised controlled evidence demonstrating a 20% relative lung cancer mortality benefit has led to endorsement of screening by several expert bodies in the US and funding by healthcare providers. Despite this pivotal result, many questions remain regarding technical and logistical aspects of screening, cost-effectiveness and generalizability to other settings. This review discusses the rationale behind screening, the results of on-going trials, potential harms of screening and current knowledge gaps.
引用
收藏
页码：S524 / S539
页数：16
相关论文
共 146 条
  • [1] Reduced Lung-Cancer Mortality with Low-Dose Computed Tomographic Screening
    Aberle, Denise R.
    Adams, Amanda M.
    Berg, Christine D.
    Black, William C.
    Clapp, Jonathan D.
    Fagerstrom, Richard M.
    Gareen, Ilana F.
    Gatsonis, Constantine
    Marcus, Pamela M.
    Sicks, JoRean D.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2011, 365 (05) : 395 - 409
  • [2] Baseline Characteristics of Participants in the Randomized National Lung Screening Trial
    Aberle, Denise R.
    Adams, Amanda M.
    Berg, Christine D.
    Clapp, Jonathan D.
    Clingan, Kathy L.
    Gareen, Ilana F.
    Lynch, David A.
    Marcus, Pamela M.
    Pinsky, Paul F.
    [J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2010, 102 (23): : 1771 - 1779
  • [3] ACRIN, ACRIN PROT
  • [4] Perifissural Nodules Seen at CT Screening for Lung Cancer
    Ahn, Myeong I.
    Gleeson, Tadhg G.
    Chan, Ida H.
    McWilliams, Annette M.
    MacDonald, Sharyn L.
    Lam, Stephen
    Atkar-Khattra, Sukhinder
    Mayo, John R.
    [J]. RADIOLOGY, 2010, 254 (03) : 949 - 956
  • [5] [Anonymous], CA CANC J CLIN, DOI DOI 10.3322/CAAC.20107
  • [6] [Anonymous], SEER CANC STAT REV 1
  • [7] Evolution of peripheral lung adenocarcinomas: CT findings correlated with histology and tumor doubling time
    Aoki, T
    Nakata, H
    Watanabe, H
    Nakamura, K
    Kasai, T
    Hashimoto, H
    Yasumoto, K
    Kido, M
    [J]. AMERICAN JOURNAL OF ROENTGENOLOGY, 2000, 174 (03) : 763 - 768
  • [8] Assessment of Radiologist Performance in the Detection of Lung Nodules: Dependence on the Definition of "Truth"
    Armato, Samuel G., III
    Roberts, Rachael Y.
    Kocherginsky, Masha
    Aberle, Denise R.
    Kazerooni, Ella A.
    MacMahon, Heber
    van Beek, Edwin J. R.
    Yankelevitz, David
    McLennan, Geoffrey
    McNitt-Gray, Michael F.
    Meyer, Charles R.
    Reeves, Anthony P.
    Caligiuri, Philip
    Quint, Leslie E.
    Sundaram, Baskaran
    Croft, Barbara Y.
    Clarke, Laurence P.
    [J]. ACADEMIC RADIOLOGY, 2009, 16 (01) : 28 - 38
  • [9] Lung cancer: Performance of automated lung nodule detection applied to cancers missed in a CT screening program
    Armato, SG
    Li, F
    Giger, ML
    MacMahon, H
    Sone, S
    Doi, K
    [J]. RADIOLOGY, 2002, 225 (03) : 685 - 692
  • [10] Australian Population Health Development Principal Committee Screening Subcommittee, 2008, TITLE ERROR
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