Real-time monitoring of the oxidative response of a membrane-channel biomimetic system to free radicals

被引：14
作者：
Liu, Yu
Ying, Yi-Lun
Wang, Hai-Yan
Cao, Chan
Li, Da-Wei
Zhang, Wen-Qing
Long, Yi-Tao [1 ]
机构：
[1] E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 59期
关键词：
DAMAGE; GENERATION;
D O I：
10.1039/c3cc41763h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel method for real-time monitoring of the oxidative response of a membrane-channel biomimetic system (MCBS) to free radicals is developed and the deduction of the buffering effect of MCBS is discussed.
引用
收藏
页码：6584 / 6586
页数：3
相关论文
共 19 条
[1]   Na+/K+-pump ligands modulate gating of palytoxin-induced ion channels [J].
Artigas, P ;
Gadsby, DC .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (02) :501-505
[2]   Protein oxidation in aging, disease, and oxidative stress [J].
Berlett, BS ;
Stadtman, ER .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (33) :20313-20316
[3]  
Cabiscol E, 2000, J BIOL CHEM, V275, P27393
[4]   Oxidative damage to DNA in diabetes mellitus [J].
Dandona, P ;
Thusu, K ;
Cook, S ;
Snyder, B ;
Makowski, J ;
Armstrong, D ;
Nicotera, T .
LANCET, 1996, 347 (8999) :444-445
[5]   FREE-RADICAL DAMAGE TO PROTEINS - THE INFLUENCE OF THE RELATIVE LOCALIZATION OF RADICAL GENERATION, ANTIOXIDANTS, AND TARGET PROTEINS [J].
DEAN, RT ;
HUNT, JV ;
GRANT, AJ ;
YAMAMOTO, Y ;
NIKI, E .
FREE RADICAL BIOLOGY AND MEDICINE, 1991, 11 (02) :161-168
[6]   The structure of the potassium channel:: Molecular basis of K+ conduction and selectivity [J].
Doyle, DA ;
Cabral, JM ;
Pfuetzner, RA ;
Kuo, AL ;
Gulbis, JM ;
Cohen, SL ;
Chait, BT ;
MacKinnon, R .
SCIENCE, 1998, 280 (5360) :69-77
[7]   LOCATION OF PEPTIDASES OUTSIDE AND INSIDE THE MEMBRANE OF STREPTOCOCCUS-CREMORIS [J].
EXTERKATE, FA .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 1984, 47 (01) :177-183
[8]   The heptameric prepore of a Staphylococcal alpha-hemolysin mutant in lipid bilayers imaged by atomic force microscopy [J].
Fang, Y ;
Cheley, S ;
Bayley, H ;
Yang, J .
BIOCHEMISTRY, 1997, 36 (31) :9518-9522
[9]   In vivo real-time measurement of superoxide anion radical with a novel electrochemical sensor [J].
Fujita, Motoki ;
Tsuruta, Ryosuke ;
Kasaoka, Shunji ;
Fujimoto, Kenji ;
Tanaka, Ryo ;
Oda, Yasutaka ;
Nanba, Masahiro ;
Igarashi, Masatsugu ;
Yuasa, Makoto ;
Yoshikawa, Toshikazu ;
Maekawa, Tsuyoshi .
FREE RADICAL BIOLOGY AND MEDICINE, 2009, 47 (07) :1039-1048
[10]   Mechanism of pyrogallol autoxidation and determination of superoxide dismutase enzyme activity [J].
Gao, RM ;
Yuan, ZB ;
Zhao, ZQ ;
Gao, XR .
BIOELECTROCHEMISTRY AND BIOENERGETICS, 1998, 45 (01) :41-45
12