Industrial relevance of thermophilic Archaea

被引:149
作者
Egorova, K [1 ]
Antranikian, G [1 ]
机构
[1] Hamburg Univ Technol, Inst Tech Microbiol, D-21073 Hamburg, Germany
关键词
D O I
10.1016/j.mib.2005.10.015
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The dramatic increase of newly isolated extremophilic microorganisms, analysis of their genomes and investigations of their enzymes by academic and industrial laboratories demonstrate the great potential of extremophiles in industrial (white) biotechnology. Enzymes derived from extremophiles (extremozymes) are superior to the traditional catalysts because they can perform industrial processes even under harsh conditions, under which conventional proteins are completely denatured. In particular, enzymes from thermophilic and hyperthermophilic Archaea have industrial relevance. Despite intensive investigations, our knowledge of the structure-function relationships of their enzymes is still limited. Information concerning the molecular properties of their enzymes and genes has to be obtained to be able to understand the mechanisms that are responsible for catalytic activity and stability at the boiling point of water.
引用
收藏
页码:649 / 655
页数:7
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