The Changing Epidemiology of Pediatric Endocarditis

被引:26
作者
Elder, Robert W. [1 ]
Baltimore, Robert S. [2 ]
机构
[1] Yale Univ, Sch Med, Pediat Cardiol Sect, New Haven, CT 06520 USA
[2] Yale Univ, Sch Med, Sch Publ Hlth, Sect Pediat Infect Dis,Dept Pediat, New Haven, CT 06520 USA
关键词
Endocarditis; Congenital heart disease; Cyanotic; Acyanotic; Streptococci; Staphylococci; Incidence; Mortality; TRANSCATHETER PULMONARY VALVE; VENTRICULAR SEPTAL-DEFECT; INFECTIVE ENDOCARDITIS; BACTERIAL-ENDOCARDITIS; DUKE CRITERIA; CHILDREN; IMPLANTATION; DIAGNOSIS; OUTCOMES; INFANTS;
D O I
10.1016/j.idc.2015.05.004
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The epidemiology of infective endocarditis (IE) appears to be related to changes in the management of children with congenital heart disease (CHD) and the virtual disappearance of rheumatic heart disease. To better understand these changes, we divide the history into: I. The pre-surgical era, II. The early years of CHD surgical intervention, correlated with introduction of antibiotics, III. The modern era of cardiac interventions. Microbiologic changes include an early predominance of viridans streptococci and an overtaking by staphylococci. Additionally, there have been advances in imaging that allow earlier detection of IE and a reduction in IE-related mortality.
引用
收藏
页码:513 / +
页数:13
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