Increasing off-time improves sleep-disordered breathing induced by vagal nerve stimulation

被引：14

作者：

Bhat, Sushanth ^{[1
]}

Lysenko, Liudmila ^{[2
]}

Neiman, Eli S. ^{[1
]}

Rao, Gautami K. ^{[1
]}

Chokroverty, Sudhansu ^{[1
]}

机构：

[1] Seton Hall Univ, NJ Neurosci Inst, JFK Med Ctr, Edison, NJ 08818 USA

[2] Ochsner Hlth Syst, New Orleans, LA USA

来源：

EPILEPTIC DISORDERS | 2012年 / 14卷 / 04期

关键词：

sleep apnea; vagal nerve stimulation; epilepsy; polysomnography; nocturnal desaturation; VNS-induced OSA; VNS off-time; REFRACTORY EPILEPSY; CHILDREN;

D O I：

10.1684/epd.2012.0534

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Vagal nerve stimulation (VNS) has been reported to adversely impact breathing in sleep. While continuous positive airway pressure is often employed to treat these patients, little data exist on the effects of adjusting various settings on VNS-induced sleep-disordered breathing. We describe a patient in whom increasing off-time caused resolution of VNS-induced arterial oxygen desaturations in sleep, which we believe is a novel observation.

引用

页码：432 / 437

页数：6

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