Drug Design Strategies for GPCR Allosteric Modulators

被引：24

作者：

Conn, P. Jeffrey ^{[1
]}

Kuduk, Scott D. ^{[2
]}

Doller, Dario ^{[3
,4
]}

机构：

[1] Vanderbilt Univ, Dept Pharmacol, Vanderbilt Ctr Neurosci Drug Discovery, Nashville, TN 37203 USA

[2] Merck Res Labs, Dept Med Chem, West Point, PA USA

[3] Lundbeck Res USA, Neuroinflarnmat Dis Biol Unit, Paramus, NJ USA

[4] Lundbeck Res DK, Discovery Chem & DMPK, Valby, Denmark

来源：

ANNUAL REPORTS IN MEDICINAL CHEMISTRY, VOL 47 | 2012年 / 47卷

关键词：

PROTEIN-COUPLED RECEPTORS; LIGANDS; MECHANISM; DISCOVERY; AGONISTS; BINDING; MGLUR5; ASSAY;

D O I：

10.1016/B978-0-12-396492-2.00028-X

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：441 / 457

页数：17

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