Prognostic value of N-terminal pro-atrial and pro-brain natriuretic peptide in patients with acute coronary syndromes

被引:130
|
作者
Omland, T [1 ]
de Lemos, JA
Morrow, DA
Antman, EN
Cannon, CP
Hall, C
Braunwald, E
机构
[1] Univ Oslo, Natl Hosp, Dept Cardiol, N-0027 Oslo 1, Norway
[2] Univ Oslo, Natl Hosp, Internal Med Res Inst, N-0027 Oslo, Norway
[3] Univ Texas, SW Med Ctr, Donald W Reynolds Cardiovasc Clin Res Unit, Dallas, TX USA
[4] Brigham & Womens Hosp, Div Cardiovasc, TIMI Study Grp, Boston, MA 02115 USA
来源
AMERICAN JOURNAL OF CARDIOLOGY | 2002年 / 89卷 / 04期
关键词
D O I
10.1016/S0002-9149(01)02271-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
From a cohort of 681 patients admitted with unstable angina and/or non-ST-segment acute myocardial infarction, baseline N-terminal pro-atrial and pro-brain natriuretic peptide (Nt-proANP and Nt-proBNP) levels were measured in 53 patients who died or experienced a new nonfatal acute myocardial infarction within 43 days of admission and in 53 age- and sex-matched control subjects. Plasma Nt-proANP and Nt-proBNP levels were both significantly related to death within 4-3 days, and for Nt-proBNP this relation remained significant after adjusting for conventional risk indicators.
引用
收藏
页码:463 / +
页数:4
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