Job insecurity and incident coronary heart disease: The Whitehall II prospective cohort study

被引：40
作者：
Ferrie, Jane E. [1 ,2 ]
Kivimaki, Mika [2 ,3 ]
Shipley, Martin J. [2 ]
Smith, George Davey [1 ,4 ]
Virtanen, Marianna [3 ]
机构：
[1] Univ Bristol, Sch Social & Community Med, Bristol BS8 2BN, Avon, England
[2] UCL, Dept Epidemiol & Publ Hlth, London, England
[3] Finnish Inst Occupat Hlth, Helsinki, Finland
[4] Univ Bristol, MRC Ctr Causal Analyses Translat Epidemiol, Bristol BS8 2BN, Avon, England
来源：
ATHEROSCLEROSIS | 2013年 / 227卷 / 01期
基金：
英国经济与社会研究理事会; 芬兰科学院; 英国医学研究理事会;
关键词：
Job insecurity; Stress; Incident coronary heart disease; Angina; Middle-aged; Prospective; ACUTE MYOCARDIAL-INFARCTION; ST-ELEVATION; FOLLOW-UP; HEALTH; CONSEQUENCES; COUNTRIES; MORTALITY; ANGINA; RATES; WOMEN;
D O I：
10.1016/j.atherosclerosis.2012.12.027
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Objective: This study uses a prospective design to examine the association between self-reported job insecurity and incident coronary heart disease; an association which has been little investigated previously. Methods: Participants were 4174 British civil servants (1236 women and 2938 men), aged 42 to 56 with self-reported data on job insecurity and free from coronary heart disease at baseline (1995-6). These participants were followed until 2002-4, an average of 8.6 years, for incident fatal coronary heart disease, clinically verified incident non-fatal myocardial infarction, or definite angina (a total of 168 events). Results: Cox proportional hazard models adjusted for socio-demographic characteristics showed job insecurity to be associated with a 1.42-fold (95% CI, 1.05-1.93) risk of incident coronary heart disease compared with secure employment. Adjustment for physiological and behavioral cardiovascular risk factors had little effect on this estimate; 1.38 (1.01-1.88). Conclusion: This study suggests that job insecurity may adversely affect coronary health. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码：178 / 181
页数：4
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