The structure of an actin-crosslinking domain from human fimbrin

被引：112

作者：

Goldsmith, SC

Pokala, M

Shen, WY

Fedorov, AA

Matsudaira, P

Almo, SC

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT BIOCHEM,BRONX,NY 10461

[2] MIT,DEPT BIOL,CAMBRIDGE,MA 02142

来源：

NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 09期

关键词：

D O I：

10.1038/nsb0997-708

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The structure of the N-terminal actin binding domain of human fimbrin offers the first view of an F-actin crosslinking protein and is representative of the conserved actin binding domain found in the largest family of crosslinking proteins. This domain is composed of two calponin homology domains and allows for the mapping of residues implicated in F-actin binding.

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页码：708 / 712

页数：5

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