Synthesis of pyrazolylvinyl ketones from furan derivatives

被引：10

作者：

Sawengngen, Nattawut ^{[1
]}

Chalikidi, Petrakis N. ^{[2
]}

Araby, Sara ^{[1
]}

Hampel, Frank ^{[3
]}

Gmeiner, Peter ^{[1
]}

Serdyuk, Olga V. ^{[1
]}

机构：

[1] Univ Erlangen Nurnberg, Inst Med Chem, Dept Chem & Pharm, Nikolaus Fiebiger Str 10, D-91058 Erlangen, Germany

[2] KL Khetagurov North Ossetian State Univ, Vatutina 43-46, Vladikavkaz 362025, Russia

[3] Univ Erlangen Nurnberg, Inst Organ Chem 1, Dept Chem & Pharm, Nikolaus Fiebiger Str 10, D-91058 Erlangen, Germany

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2019年 / 17卷 / 19期

关键词：

BIOLOGICAL EVALUATION; PYRAZOLE DERIVATIVES; CHALCONES; DESIGN; ANALOGS;

D O I：

10.1039/c9ob00701f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new protocol for the synthesis of pyrazol-5-ylvinyl ketones, e.g. pyrazole-chalcones, employing furfuryl ketones as a triketone equivalent, has been developed. The reaction occurs under mild conditions and does not require the use of expensive materials. Other important benefits include the simplicity and atom efficiency of this approach.

引用

页码：4850 / 4855

页数：6

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