Who are the persons living with HIV who might refuse to participate in HIV cure-related clinical trials with treatment interruption?

被引：7
作者：
Protiere, Christel [1 ,2 ]
Fiorentino, Marion [1 ,2 ]
Sow, Abdourahmane [1 ,2 ]
Preau, Marie [3 ]
Mora, Marion [1 ,2 ]
Fressard, Lisa [2 ,4 ,5 ]
Meyer, Laurence [6 ]
Lelievre, Jean-Daniel [7 ,8 ,9 ]
Lambotte, Olivier [10 ,11 ,12 ,13 ]
Spire, Bruno [1 ,2 ]
Suzan-Monti, Marie [1 ,2 ]
机构：
[1] Aix Marseille Univ, INSERM, SESSTIM, IRD, Marseille, France
[2] ORS PACA, Marseille, France
[3] GRePS Lyon 2 Univ Bron, Bron, France
[4] Aix Marseille Univ, IRD, AP HM, SSA,VITROME, Marseille, France
[5] IHU Mediterranee Infect, Marseille, France
[6] Univ Paris Sud 11, Hop Bicetre, AP HP, Dept Epidemiol,INSERM,U1018, Le Kremlin Bicetre, France
[7] INSERM, U955, Equipe 16, Creteil, France
[8] Univ Paris Est, Fac Med, Champs Sur Marne, France
[9] Vaccine Res Inst, F-94000 Creteil, France
[10] Hop Bicetre, AP HP, Serv Med Interne & Immunol Clin, Le Kremlin Bicetre, France
[11] INSERM, U1184, Immunol Viral Infect & Autoimmune Dis, Le Kremlin Bicetre, France
[12] Univ Paris Sud, UMR 1184, Le Kremlin Bicetre, France
[13] CEA, DSV, iMETI, IDMIT, Fontenay Aux Roses, France
来源：
AIDS | 2020年 / 34卷 / 07期
关键词：
VACCINE HESITANCY; WILLINGNESS; DESIRABILITY; WILL;
D O I：
10.1097/QAD.0000000000002530
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Achieving a HIV cure has become a research priority. As any improvement of knowledge, which could help scientists design new HIV cure-related clinical trials (HCRCT) depends on the risks potential participants are willing to accept, it is important to understand who will agree or refuse to participate and in which proportions. By providing insights into factors associated with reluctance toward HCRCT participation, our results may help clinicians in patient recruitment. © 2020 Wolters Kluwer Health, Inc. All rights reserved.
引用
收藏
页码：1095 / 1099
页数：5
相关论文
共 42 条
  • [1] Arnold MP, 2015, J VIRUS ERAD, V1, P43
  • [2] Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals
    Bar-On, Yotam
    Gruell, Henning
    Schoofs, Till
    Pai, Joy A.
    Nogueira, Lilian
    Butler, Allison L.
    Millard, Katrina
    Lehmann, Clara
    Suarez, Isabelle
    Oliveira, Thiago Y.
    Karagounis, Theodora
    Cohen, Yehuda Z.
    Wyen, Christoph
    Scholten, Stefan
    Handl, Lisa
    Belblidia, Shiraz
    Dizon, Juan P.
    Vehreschild, Joerg J.
    Witmer-Pack, Maggi
    Shimeliovich, Irina
    Jain, Kanika
    Fiddike, Kerstin
    Seaton, Kelly E.
    Yates, Nicole L.
    Horowitz, Jill
    Gulick, Roy M.
    Pfeifer, Nico
    Tomaras, Georgia D.
    Seaman, Michael S.
    Faetkenheuer, Gerd
    Caskey, Marina
    Klein, Florian
    Nussenzweig, Michel C.
    [J]. NATURE MEDICINE, 2018, 24 (11) : 1701 - +
  • [3] Past, present and future: 30 years of HIV research
    Barre-Sinoussi, Francoise
    Ross, Anna Laura
    Delfraissy, Jean-Francois
    [J]. NATURE REVIEWS MICROBIOLOGY, 2013, 11 (12) : 877 - 883
  • [4] Broadbent JJ, 2019, BMJ-BRIT MED J, V66, pl4457
  • [5] Why high-risk, non-expected-utility-maximising gambles can be rational and beneficial: the case of HIV cure studies
    Buchak, Lara
    [J]. JOURNAL OF MEDICAL ETHICS, 2017, 43 (02) : 90 - 95
  • [6] Chu CE, 2015, AIDS RES HUM RETROV, V31, P78, DOI [10.1089/aid.2014.0200, 10.1089/AID.2014.0200]
  • [7] Durable Control of HIV Infection in the Absence of Antiretroviral Therapy Opportunities and Obstacles
    Chun, Tae-Wook
    Eisinger, Robert W.
    Fauci, Anthony S.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2019, 322 (01): : 27 - 28
  • [8] Barriers and motivations for participation in preventive vaccine clinical trials: Experience of 5 clinical research sites
    Detoc, M.
    Launay, O.
    Duale, C.
    Mutter, C.
    Le Huec, J-C
    Lenzi, N.
    Lucht, F.
    Gagneux-Brunon, A.
    Botelho-Nevers, E.
    [J]. VACCINE, 2019, 37 (44) : 6633 - 6639
  • [9] Vaccine hesitancy An overview
    Dube, Eve
    Laberge, Caroline
    Guay, Maryse
    Bramadat, Paul
    Roy, Real
    Bettinger, Julie
    [J]. HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2013, 9 (08) : 1763 - 1773
  • [10] Dubé K, 2018, AIDS RES HUM RETROV, V34, P67, DOI [10.1089/aid.2017.0067, 10.1089/AID.2017.0067]
12345