BK virus associated pronounced hemorrhagic cystoureteritis after bone marrow transplantation

被引:0
作者
Haab, Alexander C. [1 ]
Keller, Isabelle S. [1 ]
Padevit, Christian [1 ]
John, Hubert [1 ]
机构
[1] Kantonsspital Winterthur, EBU Certified Training Ctr, Dept Urol, CH-8401 Winterthur, Switzerland
关键词
BK virus; hemorrhagic cystitis; bilateral nephroureterectomy; RISK-FACTORS; CYSTITIS; POLYOMAVIRUS;
D O I
暂无
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Ureteral stenosis due to reactivation of the BK virus (BKV) in a state of immunodeficiency is very rare. More common is the appearance of a hemorrhagic cystitis. This report not only shows bilateral ureteral stenosis after bone marrow transplantation, but also presents severe complications as chronic pelvic pain and impaired kidney function as well as irreparable damage to the whole urinary tract leading to nephroureterectomy, subtrigonal cystectomy and orthotopic ileal neobladder. Finally renal transplantation was required. To our knowledge this is the first case in the literature where such a severe course of BKV associated hemorrhagic cystoureteritis is described.
引用
收藏
页码:8009 / 8011
页数:3
相关论文
共 9 条
[1]   Incidence and treatment of hemorrhagic cystitis in children given hematopoietic stem cell transplantation: a survey from the Italian association of pediatric hematology oncology-bone marrow transplantation group [J].
Cesaro, S ;
Brugiolo, A ;
Faraci, M ;
Uderzo, C ;
Rondelli, R ;
Favre, C ;
Zecca, M ;
Garetto, G ;
Dini, G ;
Pillon, M ;
Messina, C ;
Zanesco, L ;
Pession, A ;
Locatelli, F .
BONE MARROW TRANSPLANTATION, 2003, 32 (09) :925-931
[2]   Polyomavirus BK infection in blood and marrow transplant recipients [J].
Dropulic, L. K. ;
Jones, R. J. .
BONE MARROW TRANSPLANTATION, 2008, 41 (01) :11-18
[3]   Rare cause of ureteral obstruction [J].
Gaston, KE ;
Gabriel, DA ;
Lavelle, JP .
UROLOGY, 2005, 66 (05) :11105-11106
[4]   Polyomavirus BK [J].
Hirsch, HH ;
Steiger, J .
LANCET INFECTIOUS DISEASES, 2003, 3 (10) :611-623
[5]  
LASZLO D, 1995, HAEMATOLOGICA, V80, P421
[6]   Clinicopathological features and risk factors of clinically overt haemorrhagic cystitis complicating bone marrow transplantation [J].
Leung, AYH ;
Mak, R ;
Lie, AKW ;
Yuen, KY ;
Cheng, VCC ;
Liang, R ;
Kwong, YL .
BONE MARROW TRANSPLANTATION, 2002, 29 (06) :509-513
[7]   Clinical course and treatment of haemorrhagic cystitis associated with BK type of human polyomavirus in nine paediatric recipients of allogeneic bone marrow transplants [J].
Peinemann, F ;
de Villiers, EM ;
Döorries, K ;
Adams, O ;
Vögeli, TA ;
Burdach, S .
EUROPEAN JOURNAL OF PEDIATRICS, 2000, 159 (03) :182-188
[8]   BK virus: A clinical review [J].
Reploeg, MD ;
Storch, GA ;
Clifford, DB .
CLINICAL INFECTIOUS DISEASES, 2001, 33 (02) :191-202
[9]   Risk factors for severe hemorrhagic cystitis following BMT [J].
Seber, A ;
Shu, XO ;
Defor, T ;
Sencer, S ;
Ramsay, N .
BONE MARROW TRANSPLANTATION, 1999, 23 (01) :35-40