Communicating chemical congregation: A molecular AND logic gate with three chemical inputs as a "lab-on-a-molecule" prototype

被引:297
作者
Magri, DC [1 ]
Brown, GJ [1 ]
McClean, GD [1 ]
de Silva, AP [1 ]
机构
[1] Queens Univ Belfast, Sch Chem & Chem Engn, Belfast BT9 5AG, Antrim, North Ireland
关键词
D O I
10.1021/ja058295+
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We demonstrate the first three-input molecular AND logic gate based on three chemical inputs as a direct way of detecting congregations of chemical species. The AND gate operates in water and responds to Na+, H+, and Zn2+ inputs with an enhanced fluorescence signal when pre-set concentration thresholds are exceeded. Future lab-on-a-molecule" devices could have application in medicine for rapid disease screening. Copyright © 2006 American Chemical Society."
引用
收藏
页码:4950 / 4951
页数:2
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