Expression pattern of nuclear p53 is unique in COS-1 cells

被引：0

作者：

Lee, JC

Lee, TS

Ho, HY

Hsueh, HC

Huang, WT

Ho, YR

Lai, MD

机构：

[1] NATL CHENG KUNG UNIV,COLL MED,DEPT BIOCHEM,TAINAN,TAIWAN

[2] NATL CHENG KUNG UNIV,COLL MED,DEPT SURG,TAINAN,TAIWAN

来源：

ANTICANCER RESEARCH | 1996年 / 16卷 / 5A期

关键词：

p53; COS-1; replication;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

As p53 is transcriptionally inactive in COS-1 cells, we felt it would be interesting to study the relative time course of expression of nuclear p53 and the onset of S phase. Our results indicated that the expression of nuclear p53 lagged behind the onset of S phase in COS-1 cells. In addition, rapid nuclear expression of p53, probably resulting from nuclear translocation, occurred immediately after the addition of serum into COS1 cells. No such phenomena were found in B104-1 and BHK cells.

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页码：2705 / 2708

页数：4

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