Cancer immunotherapy: harnessing the immune system to battle cancer

被引：997
|
作者：
Yang, Yiping [1 ,2 ]
机构：
[1] Duke Univ, Dept Med, Div Hematol Malignancies & Cellular Therapy, Durham, NC 27710 USA
[2] Duke Univ, Dept Immunol, Durham, NC 27710 USA
来源：
JOURNAL OF CLINICAL INVESTIGATION | 2015年 / 125卷 / 09期
关键词：
B7; FAMILY; T-CELLS; CTLA-4; MEMBER; IMMUNOGLOBULIN; ACTIVATION; ANTIBODY; SUPERFAMILY; LYMPHOCYTES; RECEPTOR;
D O I：
10.1172/JCI83871
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The recent clinical successes of immune checkpoint blockade and chimeric antigen receptor T cell therapies represent a turning point in cancer immunotherapy. These successes also underscore the importance of understanding basic tumor immunology for successful clinical translation in treating patients with cancer. The Reviews in this Review Series focus on current developments in cancer immunotherapy, highlight recent advances in our understanding of basic aspects of tumor immunology, and suggest how these insights can lead to the development of new immunotherapeutic strategies.
引用
收藏
页码：3335 / 3337
页数：3
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