Contemporary management of penile cancer

All patients need multidisciplinary management in cancer centres. Most cases are amenable to conservative surgery without oncological compromise. Inguinal lymph nodes are best managed according to the EAU guidelines. DSLB will hopefully be shown to match its promise of regional control with reduced morbidity, although this has yet to be realized. Randomized controlled trials are necessary to define the indications and timing of adjuvant therapy for high-risk and advanced cases. The rarity of the disease suggests that trials should be international, using consistent management strategies. © 2008 The Authors.