Improving the estimation of flow speed for laser speckle imaging with single exposure time

被引：37

作者：

Wang, Yang ^{[1
,2
]}

Wen, Dong ^{[1
,2
]}

Chen, Xiao ^{[1
,2
]}

Huang, Qin ^{[1
,2
]}

Chen, Ming ^{[1
,2
]}

Lu, Jinling ^{[1
,2
]}

Li, Pengcheng ^{[1
,2
]}

机构：

[1] Huazhong Univ Sci & Technol, Wuhan Natl Lab Optoelect, Britton Chance Ctr Biomed Photon, Wuhan 430074, Peoples R China

[2] Huazhong Univ Sci & Technol, Dept Biomed Engn, Minist Educ, Key Lab Biomed Photon, Wuhan 430074, Peoples R China

来源：

OPTICS LETTERS | 2017年 / 42卷 / 01期

基金：

中国国家自然科学基金; 国家高技术研究发展计划(863计划);

关键词：

CEREBRAL-BLOOD-FLOW; CONTRAST; SPECTROSCOPY; SKULL; SIZE;

D O I：

10.1364/OL.42.000057

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Laser speckle contrast imaging is a full-field imaging technique for measuring blood flow by mapping the speckle contrast with high spatial and temporal resolution. However, the statically scattered light from stationary tissues seriously degrades the accuracy of flow speed estimation. In this Letter, we present a simple calibration approach to calculate the proportions of dynamically scattered light and correct the effect of static scattering with single exposure time. Both the phantom and animal experimental results suggest that this calibration approach has the ability to improve the estimation of the relative blood flow in the presence of static scattering. (C) 2016 Optical Society of America.

引用

页码：57 / 60

页数：4

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