Stabilising fluorescent silica nanoparticles against dissolution effects for biological studies

被引:86
作者
Mahon, Eugene [1 ]
Hristov, Delyan R. [1 ]
Dawson, Kenneth A. [1 ]
机构
[1] Univ Coll Dublin, UCD Conway Inst Biomol & Biomed Res, Sch Chem & Chem Biol, Ctr BioNano Interact, Dublin 4, Ireland
关键词
AMORPHOUS SILICA; PARTICLE-SIZE; KINETICS; MONODISPERSE; SHAPE; SPHERES; GROWTH; MEDIA;
D O I
10.1039/c2cc34023b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Here we show that commonly employed Stober type fluorescently labelled silica nanoprobes degrade by hydrolytic dissolution, accelerated under biological media conditions as compared to water alone. We have thus developed a method to greatly improve their stability under such conditions.
引用
收藏
页码:7970 / 7972
页数:3
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