Altered Cardiac Innervation Predisposes to Ventricular Arrhythmia

被引:14
作者
Bengel, Frank M. [1 ]
Thackeray, James T. [1 ]
机构
[1] Hannover Med Sch, Klin Nukl Med, D-30625 Hannover, Germany
关键词
C-11-meta-hydroxyephedrine; myocardial viability positron; emission tomography; sudden cardiac arrest; sympathetic denervation; POSITRON-EMISSION-TOMOGRAPHY; SYMPATHETIC DENERVATION; HIBERNATING MYOCARDIUM; VIABLE MYOCARDIUM; INFARCTION; EVENTS; HEART;
D O I
10.1016/j.jacc.2013.08.1629
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The sympathetic nervous system of the heart is well known as a key modulator of cardiac physiology and electromechanical properties. Results of a wide spectrum of basic and clinical studies, as well as the therapeutic success of anti-adrenergic agents have provided proof that it plays an important role in the development and progression of cardiovascular disease. Yet, the quest for a better understanding of the clinical importance of the heart's nervous system continues, wherein novel approaches to guide and improve therapy for heart failure and ischemic heart disease are emerging.
引用
收藏
页码:150 / 152
页数:3
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