Advanced Imaging in the Evaluation of Migraine Headaches

被引:22
作者
Ellingson, Benjamin M. [1 ,2 ,3 ,4 ,5 ,6 ]
Hesterman, Chelsea [7 ]
Johnston, Mollie [7 ]
Dudeck, Nicholas R. [1 ,2 ]
Charles, Andrew C. [7 ]
Villablanca, Juan Pablo [2 ]
机构
[1] Univ Calif Los Angeles, UCLA Ctr Comp Vis & Imaging Biomarkers, David Geffen Sch Med, 924 Westwood Blvd,Suite 615, Los Angeles, CA 90024 USA
[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Radiol Sci, 924 Westwood Blvd,Suite 615, Los Angeles, CA 90024 USA
[3] Univ Calif Los Angeles, David Geffen Sch Med, Dept Psychiat & Biobehav Sci, 760 Westwood Plaza, Los Angeles, CA 90095 USA
[4] Univ Calif Los Angeles, UCLA Brain Res Inst BRI, David Geffen Sch Med, 695 Charles E Young Dr S, Los Angeles, CA 90095 USA
[5] Univ Calif Los Angeles, UCLA Brain Tumor Imaging Lab BTIL, Dept Radiol Sci, David Geffen Sch Med, 924 Westwood Blvd,Suite 615, Los Angeles, CA 90024 USA
[6] Univ Calif Los Angeles, David Geffen Sch Med, Dept Psychiat, UCLA Brain Tumor Imaging Lab BTIL, 924 Westwood Blvd,Suite 615, Los Angeles, CA 90024 USA
[7] Univ Calif Los Angeles, David Geffen Sch Med, Dept Neurol, 710 Westwood Plaza, Los Angeles, CA 90095 USA
关键词
Advanced neuroimaging; Migraine; Aura; Pain processing network; Pain matrix; CEREBRAL-BLOOD-FLOW; BRAIN-STEM ACTIVATION; CORTICAL SPREADING DEPRESSION; FAMILIAL HEMIPLEGIC MIGRAINE; MUSCLE ENERGY-METABOLISM; RESTING-STATE NETWORK; PERIAQUEDUCTAL GRAY; RESONANCE-SPECTROSCOPY; OCCIPITAL CORTEX; ABNORMAL BRAIN;
D O I
10.1016/j.nic.2019.01.009
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The use of advanced imaging in routine diagnostic practice appears to provide only limited value in patients with migraine who have not experienced recent changes in headache characteristics or symptoms. However, advanced imaging may have potential for studying the biological manifestations and pathophysiology of migraine headaches. Migraine with aura appears to have characteristic spatiotemporal changes in structural anatomy, function, hemodynamics, metabolism, and biochemistry, whereas migraine without aura produces more subtle and complex changes. Large, controlled, multicenter imaging-based observational trials are needed to confirm the anecdotal evidence in the literature and test the scientific hypotheses thought to underscore migraine pathophysiology.
引用
收藏
页码:301 / +
页数:25
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