Solid Tumor Second Primary Neoplasms: Who Is at Risk, What Can We Do?

被引：57

作者：

Oeffinger, Kevin C. ^{[1
,2
]}

Baxi, Shrujal S. ^{[1
]}

Friedman, Danielle Novetsky ^{[2
]}

Moskowitz, Chaya S. ^{[3
]}

机构：

[1] Mem Sloan Kettering Canc Ctr, Dept Med, New York, NY 10065 USA

[2] Mem Sloan Kettering Canc Ctr, Dept Pediat, New York, NY 10065 USA

[3] Mem Sloan Kettering Canc Ctr, Dept Biostat, New York, NY 10065 USA

来源：

SEMINARS IN ONCOLOGY | 2013年 / 40卷 / 06期

关键词：

BREAST-CANCER RISK; LONG-TERM SURVIVORS; ACUTE LYMPHOBLASTIC-LEUKEMIA; SQUAMOUS-CELL CARCINOMA; CORONARY-HEART-DISEASE; CHILDHOOD HODGKINS-DISEASE; PRIMARY THYROID-CANCER; FOLLOW-UP; ADULT SURVIVORS; MALIGNANT NEOPLASMS;

D O I：

10.1053/j.seminoncol.2013.09.012

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Eighteen percent of incident malignancies in the United States are a second (or subsequent) cancer. Second primary neoplasms (SPNs), particularly solid tumors, are a major cause of mortality and serious morbidity among cancer survivors successfully cured of their first cancer. Multiple etiologies may lead to a cancer survivor subsequently being diagnosed with an SPN, including radiotherapy for the first cancer, unhealthy lifestyle behaviors, genetic factors, aging, or an interaction between any of these factors. In this article, we discuss these factors and synthesize this information for use in clinical practice, including preventive strategies and screening recommendations for SPNs. (C) 2013 Elsevier Inc. All rights reserved.

引用

页码：676 / 689

页数：14

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