Multicomponent Synthesis of Dihydropyrano[2,3-c]pyrazoles Catalyzed by Zinc-Proline Complex

被引：1

作者：

Han, Zong ^{[1
]}

机构：

[1] Dongying Vocat Inst, Sch Petr & Chem Engn, Dongying 257091, Peoples R China

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2022年 / 58卷 / 09期

关键词：

dihydropyrano[2; 3-c]pyrazoles; zinc-proline complex; multicomponent reaction; one-pot synthesis; ONE-POT SYNTHESIS; REUSABLE CATALYST; EFFICIENT; DERIVATIVES; WATER; ACID;

D O I：

10.1134/S1070428022090159

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient, suitable and high yielding method has been developed for the synthesis of dihydro-pyrano-[2,3-c]pyrazoles via multicomponent one-pot domino reaction of aromatic aldehydes, malononitrile, ethyl acetoacetate, and hydrazine hydrate in the presence of a catalytic amount of zinc-proline complex Zn[L-proline](2). Atom economy, good to excellent yields, operational simplicity, and easy work-up are some of the important features of this method.

引用

页码：1297 / 1302

页数：6

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