In vivo optical-resolution photoacoustic computed tomography with compressed sensing

被引:34
作者
Meng, Jing [1 ,3 ]
Wang, Lihong V. [2 ]
Liang, Dong [1 ]
Song, Liang [1 ]
机构
[1] Chinese Acad Sci, Shenzhen Inst Adv Technol, Inst Biomed & Hlth Engn, Shenzhen 518055, Peoples R China
[2] Washington Univ, Dept Biomed Engn, St Louis, MO 63130 USA
[3] Qufu Normal Univ, Coll Comp Sci, Donggang 276826, Rizhao, Peoples R China
基金
中国国家自然科学基金;
关键词
Microcirculation - Photoacoustic microscopy - Computerized tomography - Image enhancement - Data acquisition;
D O I
10.1364/OL.37.004573
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Optical-resolution photoacoustic microscopy is becoming a powerful research tool for studying microcirculation in vivo. Moreover, ultrasonic-array-based optical-resolution photoacoustic computed tomography (OR-PACT), providing comparable resolution at an improved speed, has opened up new opportunities for studying microvascular dynamics. In this Letter, we have developed a compressed sensing with partially known support (CS-PKS) photoacoustic reconstruction strategy for OR-PACT. Compared with conventional backprojection reconstruction, the CS-PKS strategy was shown to produce high-quality in vivo OR-PACT images with threefold less measurement data, which can be leveraged to improve the data acquisition speed and costs of OR-PACT systems. (C) 2012 Optical Society of America
引用
收藏
页码:4573 / 4575
页数:3
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