Vascular Dysfunction: A Key Player in Chronic Cardio-renal Syndrome

被引：15

作者：

Tomiyama, Hirofumi ^{[1
]}

Yamashina, Akira ^{[1
]}

机构：

[1] Tokyo Med Univ, Dept Cardiol, Tokyo 1608402, Japan

来源：

INTERNAL MEDICINE | 2015年 / 54卷 / 12期

关键词：

cardio-renal syndrome; endothelial function; arterial stiffness; pressure wave reflection; heart failure; chronic kidney disease; PULSE-WAVE VELOCITY; CHRONIC KIDNEY-DISEASE; PRESERVED EJECTION FRACTION; CARDIOVASCULAR RISK-FACTORS; CENTRAL BLOOD-PRESSURE; CHRONIC HEART-FAILURE; STAGE RENAL-DISEASE; ARTERIAL STIFFNESS; ENDOTHELIAL DYSFUNCTION; HYPERTENSIVE PATIENTS;

D O I：

10.2169/internalmedicine.54.4502

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This review summarizes the current methods for the functional assessment of vascular damage (e.g., assessment of endothelial function, measurement of pulse wave velocity, and pressure wave analysis) and describes the association between vascular dysfunction and chronic cardio-renal syndrome. Vascular dysfunction may contribute to the development and progression of heart failure. Additionally, vascular dysfunction, especially increased arterial stiffness and abnormal pressure wave reflection and central hemodynamics, has been reported to accelerate renal function decline. Furthermore, renal dysfunction worsens vascular pathophysiological abnormalities. Therefore, the functional assessment of vascular damage may be useful in the management of cardio-renal syndrome.

引用

页码：1465 / 1472

页数：8

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