Spectral morphological analysis of skin lesions with a polarization multispectral dermoscope

被引:50
作者
Kapsokalyvas, Dimitrios [1 ]
Bruscino, Nicola [2 ]
Alfieri, Domenico [3 ]
de Giorgi, Vincenzo [2 ]
Cannarozzo, Giovanni [2 ]
Cicchi, Riccardo [1 ,4 ]
Massi, Daniela [5 ]
Pimpinelli, Nicola [2 ]
Pavone, Francesco S. [1 ,4 ,6 ]
机构
[1] Univ Florence, European Lab Nonlinear Spect LENS, I-50019 Sesto Fiorentino, Italy
[2] Univ Florence, Dept Crit Care Med & Surg, Div Clin Prevent & Oncol Dermatol, I-50129 Florence, Italy
[3] Light4tech Firenze Srl, I-50018 Scandicci, Italy
[4] CNR, Natl Opt Inst, I-50125 Florence, Italy
[5] Univ Florence, Dept Crit Care Med & Surg, Div Human Pathol & Oncol, I-50134 Florence, Italy
[6] Univ Florence, Dept Phys & Astron, I-50019 Sesto Fiorentino, Italy
关键词
SCATTERING PROPERTIES; IN-VIVO; EPILUMINESCENCE MICROSCOPY; LIGHT-SCATTERING; PATTERN-ANALYSIS; ABCD RULE; DIAGNOSIS; MELANOMA; TISSUES; SPECTROSCOPY;
D O I
10.1364/OE.21.004826
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Dermoscopy is the conventional technique used for the clinical inspection of human skin lesions. However, the identification of diagnostically relevant morphologies can become a complex task. We report on the development of a polarization multispectral dermoscope for the in vivo imaging of skin lesions. Linearly polarized illumination at three distinct spectral regions (470, 530 and 625 nm), is performed by high luminance LEDs. Processing of the acquired images, by means of spectral and polarization filtering, produces new contrast images, each one specific for melanin absorption, hemoglobin absorption, and single scattering. Analysis of such images could facilitate the identification of pathological morphologies. (C) 2013 Optical Society of America
引用
收藏
页码:4826 / 4840
页数:15
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