Discovery of AMG 221: An 11β-HSD1 inhibitor in the clinic for type 2 diabetes

被引：0

作者：

Fotsch, Christopher ^{[1
]}

Adams, Jeffrey ^{[2
]}

Bartberger, Michael ^{[3
]}

Bercot, Eric A. ^{[2
]}

Cai, Lynn ^{[1
]}

Castro, Victor M. ^{[4
]}

Chen, Michelle ^{[5
]}

Cupples, Rod ^{[5
]}

Emery, Maurice ^{[6
]}

Fretland, Jenne ^{[6
]}

Guram, Anil ^{[2
]}

Gustafsson, Sonja ^{[4
]}

Hague, Andrew ^{[2
]}

Hale, Clarence ^{[5
]}

Han, Nianhe ^{[1
]}

Hayashi, Michael ^{[6
]}

Henriksson, Martin ^{[4
]}

Hickman, Dean ^{[6
]}

Homan, Evert ^{[4
]}

Hungate, Randall W. ^{[1
]}

Johansson, Lars ^{[4
]}

Jordan, Steven ^{[3
]}

Kaiser, Christina ^{[4
]}

Komorowski, Renee ^{[5
]}

Li, Aiwen ^{[1
]}

Liu, Qingyian ^{[1
]}

Matsumoto, Guy ^{[6
]}

McRae, Kenneth ^{[2
]}

Moniz, George ^{[2
]}

Palm, Gunnar ^{[4
]}

Pyring, David ^{[4
]}

St. Jean, David J., Jr. ^{[1
]}

Sun, Yaxiong ^{[3
]}

Sydow-Backman, Mona ^{[4
]}

Tedenborg, Lars ^{[4
]}

Tu, Hua ^{[5
]}

Ursa, Stephania ^{[5
]}

Veniant, Murielle ^{[5
]}

Williams, Meredith ^{[4
]}

Xu, Giufen ^{[6
]}

Ye, Qiuping ^{[6
]}

Yuan, Chester ^{[1
]}

Zhang, Jiandong ^{[3
]}

Zhang, Xiping ^{[6
]}

Wang, Minghan ^{[5
]}

机构：

[1] Amgen Inc, Dept Chem Res & Discovery, Thousand Oaks, CA 91320 USA

[2] Amgen Inc, Chem Proc R&D, Thousand Oaks, CA 91320 USA

[3] Amgen Inc, Dept Mol Struct, Thousand Oaks, CA 91320 USA

[4] Biovitrum AB, SE-11276 Stockholm, Sweden

[5] Amgen Inc, Dept Metab Disorders, Thousand Oaks, CA 91320 USA

[6] Amgen Inc, Dept Pharmacokinet & Drug Metab, Thousand Oaks, CA 91320 USA

来源：

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2009年 / 237卷

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

29-MEDI

引用

页数：1

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