Amyloidosis - the Importance of an Early Diagnosis

被引:0
作者
Moraru, Despina [1 ]
Suceveanu, Adrian Paul [1 ]
Pantea-Stoian, Anca [2 ]
Nitipir, Cornelia [2 ]
Mazilu, Laura [1 ]
Diaconu, Camelia Cristina [2 ]
Hainarosie, Razvan [2 ]
Pituru, Silviu [2 ]
Voinea, Felix [1 ]
Timofte, Daniel [3 ]
Suceveanu, Andra Iulia [1 ]
机构
[1] Ovidius Univ, Emergency Hosp Constanta, Fac Med, Constanta, Romania
[2] Carol Davila Univ Med & Pharm, Bucharest, Romania
[3] Grigore T Popa Univ Med & Pharm, Dept Surg Sci, Iasi, Romania
来源
PROCEEDINGS OF THE 35TH BALKAN MEDICAL WEEK | 2018年
关键词
amyloidosis; rare disease; non-specific symptoms; PRIMARY SYSTEMIC AMYLOIDOSIS; STEM-CELL TRANSPLANTATION; LIGHT-CHAINS; SERUM; CHEMOTHERAPY; COMPONENT; FEATURES; THERAPY; TUMOR;
D O I
暂无
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Amyloidosis is a generic label that refers to a group of rare, severe conditions caused by extracellular and tisular deposition of an abnormal protein called amyloid, in tissues and organs. This paper aims to highlight the importance of a high level of suspicion in diagnosing this category of patients that frequently present with non-specific symptoms. Better recognition of amyloidosis allows for earlier treatment and improved outcomes. Amyloidosis should be considered in patients without cause of hepatomegaly, jaundice, macroglossia, proteinuria, cardiac insufficiency, neuropathy, and in atypical cases of multiple myeloma.
引用
收藏
页码:182 / 187
页数:6
相关论文
共 32 条
  • [1] Quantitative analysis of serum free light chains - A new marker for the diagnostic evaluation of primary systemic amyloidosis
    Abraham, RS
    Katzmann, JA
    Clark, RJ
    Bradwell, AR
    Kyle, RA
    Gertz, MA
    [J]. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2003, 119 (02) : 274 - 278
  • [2] Role of imaging in the diagnosis and management of patients with cardiac amyloidosis: State of the art review and focus on emerging nuclear techniques
    AlJaroudi, Wael A.
    Desai, Milind Y.
    Tang, W. H. Wilson
    Phelan, Dermot
    Cerqueira, Manuel D.
    Jaber, Wael A.
    [J]. JOURNAL OF NUCLEAR CARDIOLOGY, 2014, 21 (02) : 271 - 283
  • [3] Therapeutic advances demand accurate typing of amyloid deposits
    Anesi, E
    Palladini, G
    Perfetti, V
    Arbustini, E
    Obici, L
    Merlini, G
    [J]. AMERICAN JOURNAL OF MEDICINE, 2001, 111 (03) : 243 - 244
  • [4] Asl KH, 1999, J IMMUNOL, V162, P5556
  • [5] NEUROENDOCRINE RENAL CARCINOMA THERAPEUTIC AND DIAGNOSTIC ISSUES
    Badiu, C. D.
    Nita, G. Rahnea
    Ciuhu, A. N.
    Manea, C.
    Smarandache, C. G.
    Georgescu, D. G.
    Bedereag, S. I.
    Cocosila, C. L.
    Braticevici, B.
    Mehedintu, C.
    Grigorean, V. T.
    [J]. ACTA ENDOCRINOLOGICA-BUCHAREST, 2016, 12 (03) : 355 - 361
  • [6] Betova T. M., 2018, ARCH BALK MED UNION, V53, P463
  • [7] Bodean O, 2018, REV CHIM-BUCHAREST, V69, P1411
  • [8] Bratu OG, 2018, REV CHIM-BUCHAREST, V69, P1813
  • [9] EVALUATION OF CELLULAR IMMUNE FUNCTION AND GASTRIC TUMOUR FOR BIOMARKERS AFTER EARLY ENTERAL NUTRITION
    Bu, Xianmin
    Xu, Fangfang
    Ma, Jie
    Wei, Li
    [J]. FARMACIA, 2018, 66 (04) : 615 - 620
  • [10] ELECTRON MICROSCOPIC OBSERVATIONS ON A FIBROUS COMPONENT IN AMYLOID OF DIVERSE ORIGINS
    COHEN, AS
    CALKINS, E
    [J]. NATURE, 1959, 183 (4669) : 1202 - 1203