Myelodysplastic Syndromes

被引:73
作者
Greenberg, Peter L. [1 ]
Attar, Eyal [2 ]
Bennett, John M. [3 ]
Bloomfield, Clara D. [3 ]
Borate, Uma [4 ]
De Castro, Carlos M.
Deeg, H. Joachim
Frankfurt, Olga [5 ]
Gaensler, Karin
Garcia-Manero, Guillermo [6 ]
Gore, Steven D. [7 ]
Head, David [8 ]
Komrokji, Rami
Maness, Lori J. [9 ]
Millenson, Michael [10 ]
O'Donnell, Margaret R.
Shami, Paul J. [11 ]
Stein, Brady L. [12 ]
Stone, Richard M.
Thompson, James E. [13 ]
Westervelt, Peter [14 ]
Wheeler, Benton [15 ]
Shead, Dorothy A.
Naganuma, Maoko
机构
[1] Stanford Canc Inst, Stanford, CA USA
[2] Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02114 USA
[3] Ohio State Univ, Ctr Comprehens Canc, James Canc Hosp, Inst Res, Columbus, OH 43210 USA
[4] Univ Alabama, Ctr Comprehens Canc, Tuscaloosa, AL 35487 USA
[5] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA
[6] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[7] Sidney Kimmel Comprehens Canc Ctr, Sidney, BC, Canada
[8] Vanderbilt Ingram Canc Ctr, Nashville, TN USA
[9] Univ Nebraska Med Ctr, UNMC Eppley Canc Ctr, Omaha, NE USA
[10] Fox Chase Canc Ctr, Philadelphia, PA 19111 USA
[11] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA
[12] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA
[13] Roswell Pk Canc Inst, Buffalo, NY USA
[14] Washington Univ, Sch Med, Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO 63130 USA
[15] Univ Tennessee, Hlth Sci Ctr, St Jude Childrens Res Hosp, Knoxville, TN 37996 USA
来源
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2013年 / 11卷 / 07期
关键词
D O I
10.6004/jnccn.2013.0104
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal hematopoietic disorders characterized by cytopenias, dysplasia in one or more myeloid lineages, and the potential for development of acute myeloid leukemia. These disorders primarily affect older adults. The NCCN Clinical Practice Guidelines in Oncology for MDS provide recommendations on the diagnostic evaluation and classification of MDS, risk evaluation according to established prognostic assessment tools (including the new revised International Prognostic Scoring System), treatment options according to risk categories, and management of related anemia.
引用
收藏
页码:838 / 874
页数:37
相关论文
共 183 条
[11]  
[Anonymous], 2008, WHO CLASSIFICATION T
[12]   Response to imatinib mesylate in patients with chronic myeloproliferative diseases with rearrangements of the platelet-derived growth factor receptor beta [J].
Apperley, JF ;
Gardembas, M ;
Melo, JV ;
Russell-Jones, R ;
Bain, BJ ;
Baxter, J ;
Chase, A ;
Chessells, JM ;
Colombat, M ;
Dearden, CE ;
Dimitrijevic, S ;
Mahon, FX ;
Marin, D ;
Nikolova, Z ;
Olavarria, E ;
Silberman, S ;
Schultheis, B ;
Cross, NCP ;
Goldman, JM .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (07) :481-487
[13]  
Atallah E, 2012, BLOOD, V120
[14]   Multiparameter Flow Cytometry for the Diagnosis and Monitoring of Small GPI-Deficient Cellular Populations [J].
Battiwalla, Minoo ;
Hepgur, Mehmet ;
Pan, Dalin ;
McCarthy, Philip L. ;
Ahluwalia, Manmeet S. ;
Camacho, Susan H. ;
Starostik, Petr ;
Wallace, Paul K. .
CYTOMETRY PART B-CLINICAL CYTOMETRY, 2010, 78B (05) :348-356
[15]   Novel translocations that disrupt the platelet-derived growth factor receptor β (PDGFRB) gene in BCR-ABL-negative chronic myeloproliferative disorders [J].
Baxter, EJ ;
Kulkarni, S ;
Vizmanos, JL ;
Jaju, R ;
Martinelli, G ;
Testoni, N ;
Hughes, G ;
Salamanchuk, Z ;
Calasanz, MJ ;
Lahortiga, I ;
Pocock, CF ;
Dang, R ;
Fidler, C ;
Wainscoat, JS ;
Boultwood, J ;
Cross, NCP .
BRITISH JOURNAL OF HAEMATOLOGY, 2003, 120 (02) :251-256
[16]   Validation of a Prognostic Model and the Impact of Mutations in Patients With Lower-Risk Myelodysplastic Syndromes [J].
Bejar, Rafael ;
Stevenson, Kristen E. ;
Caughey, Bennett A. ;
Abdel-Wahab, Omar ;
Steensma, David P. ;
Galili, Naomi ;
Raza, Azra ;
Kantarjian, Hagop ;
Levine, Ross L. ;
Neuberg, Donna ;
Garcia-Manero, Guillermo ;
Ebert, Benjamin L. .
JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (27) :3376-3382
[17]   THE CHRONIC MYELOID LEUKEMIAS - GUIDELINES FOR DISTINGUISHING CHRONIC GRANULOCYTIC, ATYPICAL CHRONIC MYELOID, AND CHRONIC MYELOMONOCYTIC LEUKEMIA - PROPOSALS BY THE FRENCH-AMERICAN-BRITISH-COOPERATIVE-LEUKEMIA-GROUP [J].
BENNETT, JM ;
CATOVSKY, D ;
DANIEL, MT ;
FLANDRIN, G ;
GALTON, DAG ;
GRALNICK, H ;
SULTAN, C ;
COX, C .
BRITISH JOURNAL OF HAEMATOLOGY, 1994, 87 (04) :746-754
[18]  
Beran M, 2001, CANCER-AM CANCER SOC, V92, P1999, DOI 10.1002/1097-0142(20011015)92:8<1999::AID-CNCR1538>3.0.CO
[19]  
2-B
[20]   Guidelines for the Diagnosis and Monitoring of Paroxysmal Nocturnal Hemoglobinuria and Related Disorders by Flow Cytometry [J].
Borowitz, Michael J. ;
Craig, Fiona E. ;
DiGiuseppe, Joseph A. ;
Illingworth, Andrea J. ;
Rosse, Wendell ;
Sutherland, D. Robert ;
Wittwer, Carl T. ;
Richards, Stephen J. .
CYTOMETRY PART B-CLINICAL CYTOMETRY, 2010, 78B (04) :211-228