Identification of a methioninase inhibitor, myrsinoic acid B, from Myrsine seguinii Lev., and its inhibitory activities

被引：13
|
作者：
Ito, Satomi [1 ]
Narise, Atsushi [1 ]
Shimura, Susumu [1 ]
机构：
[1] Lotte Co Ltd, Cent Lab, Minami Ku, Saitama 3368601, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2008年 / 72卷 / 09期
关键词：
methyl mercaptan; methioninase; myrsinoic acid B; Myrsine seguinii; taimin-tachibana;
D O I：
10.1271/bbb.80045
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A methioninase inhibitor from Myrsine seguinii was purified and identified as myrsinoic acid B. Its inhibitory activities as to crude methioninase from periodontal bacteria such as Fusobacterium nucleatum, Porphyromonas gingivalis, and Treponema denticola were determined. The IC50 values were 10.5, 82.4, and 30.3 mu M respectively.
引用
收藏
页码：2411 / 2414
页数：4
相关论文
共 41 条
  • [31] Isolation of methyl syringate as a specific aflatoxin production inhibitor from the essential oil of Betula alba and aflatoxin production inhibitory activities of its related compounds (vol 153, pg 339, 2012)
    Jermnak, Usuma
    Yoshinari, Tomoya
    Sugiyama, Yasumasa
    Tsuyuki, Rie
    Nagasawa, Hiromichi
    Sakuda, Shohei
    INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 2014, 187 : 83 - 83
  • [32] Identification and inhibitory activities of ellagic acid- and kaempferol-derivatives from Mongolian oak cups against α-glucosidase, α-amylase and protein glycation linked to type II diabetes and its complications and their influence on HepG2 cells' viability
    Yin, Peipei
    Yang, Lingguang
    Xue, Qiang
    Yu, Miao
    Yao, Fan
    Sun, Liwei
    Liu, Yujun
    ARABIAN JOURNAL OF CHEMISTRY, 2018, 11 (08) : 1247 - 1259
  • [33] PURIFICATION, INHIBITORY PROPERTIES, AMINO-ACID-SEQUENCE AND IDENTIFICATION OF THE REACTIVE-SITE OF A NEW SERINE PROTEINASE-INHIBITOR FROM OIL-RAPE (BRASSICA-NAPUS) SEED
    CECILIANI, F
    BORTOLOTTI, F
    MENEGATTI, E
    RONCHI, S
    ASCENZI, P
    PALMIERI, S
    FEBS LETTERS, 1994, 342 (02) : 221 - 224
  • [34] Isolation of Betulinic Acid, its Methyl Ester and Guaiane Sesquiterpenoids with Protein Tyrosine Phosphatase 1B Inhibitory Activity from the Roots of Saussurea lappa CBClarke
    Choi, Ji Young
    Na, MinKyun
    Hwang, In Hyun
    Lee, Seung Ho
    Bae, Eun Young
    Kim, Bo Yeon
    Ahn, Jong Seog
    MOLECULES, 2009, 14 (01) : 266 - 272
  • [35] Isolation and Identification of a Potent PTP1B Inhibitor, Ursolic Acid, from Carolina Jasmine (Gelsemium sempervirens (L.) J.St.-Hil.)
    Noshita, Toshiro
    Kakizoe, Yusuke
    Tanabe, Satoshi
    Ouchi, Hidekazu
    Tai, Akihiro
    LETTERS IN ORGANIC CHEMISTRY, 2020, 17 (12) : 939 - 943
  • [36] ISOLATION AND IDENTIFICATION OF A PLANT-GROWTH INHIBITOR, AZETIDINE-2-CARBOXYLIC ACID, FROM CLAVARIA-MIYABENA-S-ITO AND ITS OCCURRENCE IN FAMILY CLAVARIACEAE
    IKEDA, M
    NAGANUMA, Y
    OHTA, K
    SASSA, T
    MIURA, Y
    JOURNAL OF THE AGRICULTURAL CHEMICAL SOCIETY OF JAPAN, 1977, 51 (08): : 519 - 522
  • [37] A novel potent inhibitor of 2-amino-l-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) formation from Chinese chive: Identification, inhibitory effect and action mechanism
    Wang, Qi
    Cheng, Weiwei
    Zhang, Yifeng
    Kang, Qingzheng
    Gowd, Vemana
    Ren, Yuanyuan
    Chen, Feng
    Cheng, Ka-Wing
    FOOD CHEMISTRY, 2021, 345
  • [38] Affinity-Guided Isolation and Identification of Procyanidin B2 from Mangosteen (Garcinia mangostana L.) Rinds and its In Vitro LPS Binding and Neutralization Activities
    Zheng, Xinchuan
    Yang, Yongjun
    Lu, Yongling
    Chen, Qian
    PLANT FOODS FOR HUMAN NUTRITION, 2021, 76 (04) : 442 - 448
  • [39] Affinity-Guided Isolation and Identification of Procyanidin B2 from Mangosteen (Garcinia mangostana L.) Rinds and its In Vitro LPS Binding and Neutralization Activities
    Xinchuan Zheng
    Yongjun Yang
    Yongling Lu
    Qian Chen
    Plant Foods for Human Nutrition, 2021, 76 : 442 - 448
  • [40] Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure-activity relationships, molecular modeling and impact on its folk medicinal uses
    Ebada, Sherif S.
    Al-Jawabri, Nariman A.
    Youssef, Fadia S.
    El-Kashef, Dina H.
    Knedel, Tim-Oliver
    Albohy, Amgad
    Korinek, Michal
    Hwang, Tsong-Long
    Chen, Bing-Hung
    Lin, Guan-Hua
    Lin, Chia-Yi
    Aldalaien, Sa'ed M.
    Disi, Ahmad M.
    Janiak, Christoph
    Proksch, Peter
    RSC ADVANCES, 2020, 10 (62) : 38128 - 38141
12345