Gold Nanoparticles Decorated Titanium Oxide Nanotubes with Enhanced Antibacterial Activity Driven by Photocatalytic Memory Effect

被引:11
作者
Zhu, Hongqin [1 ]
Tan, Ji [2 ]
Qiu, Jiajun [2 ]
Wang, Donghui [2 ,3 ]
Zhao, Zhe [1 ]
Lu, Zihan [1 ]
Huang, Gaoshan [1 ]
Liu, Xuanyong [2 ]
Mei, Yongfeng [1 ]
机构
[1] Fudan Univ, Dept Mat Sci, State Key Lab ASIC & Syst, Shanghai 200433, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China
[3] Hebei Univ Technol, Sch Hlth Sci & Biomed Engn, Tianjin 300130, Peoples R China
基金
中国国家自然科学基金;
关键词
biomaterials; nanoparticles; porous materials; sputtering; TIO2; NANOTUBES; TOXICITY; PHOTOACTIVITY; GENERATION; COMPOSITE; FILMS;
D O I
10.3390/coatings12091351
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Titanium and its alloys have been widely used for orthopedic and dental implants. However, implant failures often occur due to the implant-related bacterial infections. Herein, titanium oxide nanotubes (TNTs) with an average diameter of 75 nm were formed by anodizing on the surface of titanium, and subsequently gold (Au) nanoparticles were deposited on TNTs by magnetron sputtering (Au@TNTs). The antibacterial study shows that TNTs surface decorated with Au nanoparticles exhibits the preferable effect in restricting the growth of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) even under dark conditions, and the antibacterial rates reached 84% and 75%, respectively. In addition, the constructed film showed no cytotoxicity. Such a selective bactericidal effect of Au@TNTs samples might be attributed to the photocatalytic memory effect, which provides a new insight in the designing of antibacterial surfaces for biomedical application.
引用
收藏
页数:10
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