Biomonitoring of trace elements in urine samples of children from a coal-mining region

被引:45
作者
dos Santos, Marina [1 ,2 ]
Flores Soares, Maria Cristina [1 ,2 ]
Martins Baisch, Paulo Roberto [1 ,3 ]
Muccillo Baisch, Ana Luiza [1 ,2 ]
Rodrigues da Silva Junior, Flavio Manoel [1 ,2 ]
机构
[1] Fac Med FAMED, Programa Posgrad Ciencias Saude, Rua Visconde Paranagua 102, BR-96203900 Rio Grande, RS, Brazil
[2] Univ Fed Rio Grande, FURG, ICB, Lab Ensaios Farmacol & Toxicol, Rio Grande, RS, Brazil
[3] Univ Fed Rio Grande, FURG, Lab Geoquim Ambiental, Rio Grande, Brazil
关键词
Human biomonitoring; Urinary levels; Schoolchildren; Environmental pollutants; REFERENCE VALUES; SELENIUM STATUS; ICP-MS; POPULATION; EXPOSURE; BLOOD; BIOMARKERS; CADMIUM; LEAD; RESIDENTS;
D O I
10.1016/j.chemosphere.2018.01.082
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Biomonitoring through urine samples is important for evaluating environmental exposure, since urine is the main form of excretion for most chemical elements. Children are considered more vulnerable to adverse environmental conditions, especially children in developing countries. This study aimed to biomonitor trace elements in urine samples in children from a coal-mining region in the extreme south of Brazil. A cross-sectional study was conducted on 96 children between 6 and 11 years of age. Socioeconomic data and urine samples were collected to estimate the concentration of iron, zinc, selenium, lead, and cadmium. The prevalence of metals above the reference values was 52.0% for Se, followed by 15.6% for Zn. The data point toward a vulnerability to adverse environmental conditions in these children. Although the concentrations of the elements did not reveal intoxication cases, biomonitoring should be carried out continuously in order to assess exposure to metals and ensure the health of the population. This article provides data that help determine natural levels of metallic elements in children, specifically in South America, which have not yet been established. (C) 2018 Elsevier Ltd. All tights reserved.
引用
收藏
页码:622 / 626
页数:5
相关论文
共 42 条
[1]  
ABEP 2014-Associacao Brasileira de Empresas de Pesquisa, 2013, DAD COM BAS LEV SOC
[2]   Evaluation of Essential Trace and Toxic Elements in Biological Samples of Normal and Night Blindness Children of Age Groups 3-7 and 8-12 Years [J].
Afridi, Hassan Imran ;
Kazi, Tasneem Gul ;
Kazi, Naveed ;
Kandhro, Ghulam Abbas ;
Baig, Jameel Ahmed ;
Shah, Abdul Qadir ;
Wadhwa, Sham Kumar ;
Khan, Sumaira ;
Kolachi, Nida Fatima ;
Shah, Faheem ;
Jamali, Mohammad Khan ;
Arain, Mohammad Balal ;
Sirajuddin .
BIOLOGICAL TRACE ELEMENT RESEARCH, 2011, 143 (01) :20-40
[3]   Urinary levels of arsenic and heavy metals in children and adolescents living in the industrialised area of Ria of Huelva (SW Spain) [J].
Aguilera, Inmaculada ;
Daponte, Antonio ;
Gil, Fernando ;
Hernandez, Antonio F. ;
Godoy, Patricia ;
Pla, Antonio ;
Luis Ramos, Juan .
ENVIRONMENT INTERNATIONAL, 2010, 36 (06) :563-569
[4]  
[Anonymous], 1978, BRASIL NORM REG NR 7
[5]  
[Anonymous], 2009, National Health and Nutrition Examination Survey
[6]  
ATSDR, 2017, TOXICOLOGICAL PROFIL
[7]   Susceptibility of children to environmental toxic substances [J].
Au, WW .
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2002, 205 (06) :501-503
[8]   Behavioural development of school-aged children who live around a multi-metal sulphide mine in Guangdong province, China: a cross-sectional study [J].
Bao, Qing-Song ;
Lu, Ci-Yong ;
Song, Hong ;
Wang, Mao ;
Ling, Wenhua ;
Chen, Wei-Qing ;
Deng, Xue-Qing ;
Hao, Yuan-Tao ;
Rao, Shaoqi .
BMC PUBLIC HEALTH, 2009, 9
[9]   GerES IV Pilot Study: Assessment of the exposure of German children to organophosphorus and pyrethroid pesticides [J].
Becker, Kerstin ;
Seiwert, Margarete ;
Angerer, Juergen ;
Kolossa-Gehring, Marike ;
Hoppe, Hans-Wolfgang ;
Ball, Michael ;
Schulz, Christine ;
Thumulla, Joerg ;
Seifert, Bernd .
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2006, 209 (03) :221-233
[10]   Biomarkers of metal toxicity in population studies: Research potential and interpretation issues [J].
Bernard, Alfred .
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 2008, 71 (18) :1259-1265