Full-range ultrahigh-resolution spectral-domain optical coherence tomography in 1.7 μm wavelength region for deep-penetration and high-resolution imaging of turbid tissues

被引：10

作者：

Kawagoe, Hiroyuki ^{[1
]}

Yamanaka, Masahito ^{[1
]}

Makita, Shuichi ^{[2
]}

Yasuno, Yoshiaki ^{[2
]}

Nishizawa, Norihiko ^{[1
]}

机构：

[1] Nagoya Univ, Dept Quantum Engn, Nagoya, Aichi 4648603, Japan

[2] Univ Tsukuba, Computat Opt Grp, Tsukuba, Ibaraki 3058573, Japan

来源：

APPLIED PHYSICS EXPRESS | 2016年 / 9卷 / 12期

关键词：

HIGH-SPEED; EX-VIVO; DEPTH; EYE; NM;

D O I：

10.7567/APEX.9.127002

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

For the first time, we developed a full-range ultrahigh-resolution (UHR) spectral-domain optical coherence tomography (SD-OCT) technique working in the 1.7 mu m wavelength region. This technique allowed high-resolution, deep-tissue imaging. By using a supercontinuum source operating at a wavelength of 1.7 mu m, an axial resolution of 3.6 mu m in a tissue specimen was achieved. To enhance the imaging depth of UHR-SDOCT, we performed full-range OCT imaging based on a phase modulation method. We demonstrated the three-dimensional (3D) imaging of a mouse brain with the developed system, and specific structures in the mouse brain were clearly visualized at depths up to 1.7 mm. (C) 2016 The Japan Society of Applied Physics.

引用

页数：4

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