Splenic infarction in a child with primary Epstein-Barr virus infection

被引：9

作者：

Gang, Mi Hyeon ^{[1
]}

Kim, Jae Young ^{[1
]}

机构：

[1] Chungnam Natl Univ, Sch Med, Dept Pediat, Taejon 301747, South Korea

来源：

PEDIATRICS INTERNATIONAL | 2013年 / 55卷 / 05期

关键词：

Epstein-Barr virus infection; protein C and protein S; splenic infarction; TRANSIENT ANTIPHOSPHOLIPID ANTIBODIES; MONONUCLEOSIS; PATIENT;

D O I：

10.1111/ped.12143

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Described herein is the case of a previously healthy 7-year-old girl who had splenic infarction. This lesion was identified 1 day after the first presentation of peri-umbilical and right upper quadrant pain. She had abnormal hepatic function and mild splenomegaly, and was diagnosed as having primary Epstein-Barr virus (EBV) infection. Coagulation profiles indicated low plasma activity of protein C (49%) and protein S (47%), which normalized 3 weeks later. Hypercoagulability in transient protein C and protein S deficiency might contribute to the development of splenic infarction in infectious mononucleosis.

引用

页码：E126 / E128

页数：3

共 12 条

[1] Splenic infarction: 10 years of experience [J].

Antopolsky, Meir ;

Hiller, Nurit ;

Salameh, Shaden ;

Goldshtein, Beth ;

Stalnikowicz, Ruth .

AMERICAN JOURNAL OF EMERGENCY MEDICINE, 2009, 27 (03) :262-265

[2] Splenic infarction in a patient hereditary spherocytosis, protein C deficiency and acute infectious mononucleosis [J].

Breuer, Christian ;

Janssen, Gisela ;

Laws, Hans Juergen ;

Schaper, Joerg ;

Mayatepek, Ertan ;

Schroten, Horst ;

Tenebaum, Tobias .

EUROPEAN JOURNAL OF PEDIATRICS, 2008, 167 (12) :1449-1452

[3] Splenic infarction, warm autoimmune hemolytic anemia and antiphospholipid antibodies in a patient with infectious mononucleosis [J].

Cull, Elizabeth ;

Stein, Brady L. .

INTERNATIONAL JOURNAL OF HEMATOLOGY, 2012, 95 (05) :573-576

[4] Infections and the Antiphospholipid Syndrome [J].

Garcia-Carrasco, Mario ;

Galarza-Maldonado, Claudio ;

Mendoza-Pinto, Claudia ;

Escarcega, Ricardo O. ;

Cervera, Ricard .

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2009, 36 (2-3) :104-108

[5] CT MANIFESTATIONS OF INFECTIOUS-MONONUCLEOSIS [J].

GARTEN, AJ ;

MENDELSON, DS ;

HALTON, KP .

CLINICAL IMAGING, 1992, 16 (02) :114-116

[6]

JAROCH MT, 1986, SURGERY, V100, P743

[7] Epstein-Barr virus [J].

Junker, AK .

PEDIATRICS IN REVIEW, 2005, 26 (03) :79-84

[8]

Mackenzie DC, 2012, J EMERGENCY MED, V12, P1

[9] Epstein-Barr virus - recent advances [J].

Macsween, KF ;

Crawford, DH .

LANCET INFECTIOUS DISEASES, 2003, 3 (03) :131-140

[10]

Trevenzoli M, 2001, SCAND J INFECT DIS, V33, P550, DOI 10.1080/00365540110026629

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