Association study of BDNF with completed suicide in the Japanese population

被引：19

作者：

Ratta-apha, Woraphat ^{[1
]}

Hishimoto, Akitoyo ^{[1
]}

Yoshida, Masakuni ^{[1
]}

Ueno, Yasuhiro ^{[2
]}

Asano, Migiwa ^{[3
]}

Shirakawa, Osamu ^{[4
]}

Sora, Ichiro ^{[1
]}

机构：

[1] Kobe Univ, Grad Sch Med, Chuo Ku, Dept Psychiat, Kobe, Hyogo 6500017, Japan

[2] Kobe Univ, Grad Sch Med, Dept Legal Med, Kobe, Hyogo 6500017, Japan

[3] Ehime Univ, Grad Sch Med, Dept Legal Med, Matsuyama, Ehime 790, Japan

[4] Kinki Univ, Sch Med, Dept Neuropsychiat, Osaka 589, Japan

来源：

PSYCHIATRY RESEARCH | 2013年 / 209卷 / 03期

关键词：

Brain-derived neurotrophic factor; Suicide; Association study; GENETIC-POLYMORPHISM; MOOD DISORDERS; BEHAVIOR;

D O I：

10.1016/j.psychres.2013.05.030

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

We explored the association between the brain-derived neurotrophic factor gene with suicide using 307 Japanese completed suicides, 380 healthy controls, and data from previously published samples. The meta-analyses of the valine with methionine in codon 66 (Val66Met) single nucleotide polymorphism (SNP) showed that the Met-allele tended to be associated with attempted suicide in Asian populations, but not with the completed suicide. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

引用

页码：734 / 736

页数：3

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