Cobb Syndrome: A Case Report and Systematic Review of the Literature

被引：22

作者：

Clark, Marissa Tubridy ^{[2
]}

Brooks, Emma L. ^{[2
]}

Chong, Winston ^{[3
]}

Pappas, Chris ^{[2
]}

Fahey, Michael ^{[1
,2
]}

机构：

[1] Monash Univ, Dept Paediat, Melbourne, Vic 3168, Australia

[2] Monash Med Ctr, Dept Paediat, Melbourne, Vic, Australia

[3] Monash Med Ctr, Intervent Neuroradiol Unit, Melbourne, Vic, Australia

来源：

PEDIATRIC NEUROLOGY | 2008年 / 39卷 / 06期

关键词：

D O I：

10.1016/j.pediatrneurol.2008.08.001

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report on a case of Cobb syndrome, a rare meta-meric disorder, characterized by a vascular abnormality of the spinal cord, with an associated vascular skin lesion of the same metamere, in an 8-year-old girl presenting with leg weakness. Magnetic resonance imaging revealed a spinal arteriovenous malformation at the level of T-10-L-5. This finding, together with a large, pigmented nevus at this level, is diagnostic for Cobb syndrome. A systematic review of the literature on Cobb syndrome, with a focus on treatment and outcomes, is presented. Current treatment options include combinaations of embolization, neurosurgical intervention, corticosteroid therapy, and radiotherapy. (C) 2008 by Elsevier Inc. All rights reserved.

引用

页码：423 / 425

页数：3

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