Growth inhibition of Euphorbia extract on breast cancer cell line MCF-7

被引：0

作者：

Wang, Qinwen ^{[1
]}

Yang, Guiqing ^{[2
]}

Zhang, Wenhua ^{[2
]}

Wan, Lingqin ^{[2
]}

Lin, Sixiang ^{[2
]}

Wang, Yishan ^{[2
]}

机构：

[1] Acad Mil Med Sci, Hosp Affliated 307, Dept Radiotherapy, Beijing, Peoples R China

[2] Peoples Liberat Army, Hosp 107, Ctr Tumor Treatment, Yantai, Shandong, Peoples R China

来源：

BIOTECHNOLOGY, AGRICULTURE, ENVIRONMENT AND ENERGY | 2015年

关键词：

Euphorbia extract; MCF-7; apoptosis; G2/M;

D O I：

暂无

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The objective of the present study was to observe the growth inhibition of Euphorbia extract on breast cancer cell line MCF-7 and to explore its possible mechanism. Methods: MTT assay the growth inhibition rate of Euphorbia extract on breast cancer cell line MCF-7, experimental observation Euphorbia extract on breast cancer cell line MCF-7 survival by colony formation test. Flow cytometry was used to detect the changes of Stellera chamaejasme extract liquid after tumor cell cycle. Results: Euphorbia extract on breast cancer cell line MCF-7 significantly inhibited the growth, flow cytometry PI staining was measured Euphorbia extract can improve MCF-7 G2/M phase cell number. Conclusion: Euphorbia extract can be achieved by changing the cell cycle of breast cancer cell line MCF-7 and growth inhibition.

引用

页码：129 / 131

页数：3

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