Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI

被引:99
作者
Keller, Sune H. [1 ]
Holm, Soren [1 ]
Hansen, Adam E. [1 ]
Sattler, Bernhard [2 ]
Andersen, Flemming [1 ]
Klausen, Thomas L. [1 ]
Hojgaard, Liselotte [1 ]
Kjaer, Andreas [1 ]
Beyer, Thomas [1 ,3 ]
机构
[1] Copenhagen Univ Hosp, Dept Clin Physiol Nucl Med & PET, Rigshosp, DK-2100 Copenhagen, Denmark
[2] Univ Hosp Leipzig, Dept Nucl Med, Leipzig, Germany
[3] Cmi Experts GmbH, Zurich, Switzerland
关键词
PET/MRI; MR-based attenuation correction; Image artifacts; Pitfalls; SEGMENTATION; TOMOGRAPHY;
D O I
10.1007/s10334-012-0345-4
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Integrated whole-body PET/MRI tomographs have become available. PET/MR imaging has the potential to supplement, or even replace combined PET/CT imaging in selected clinical indications. However, this is true only if methodological pitfalls and image artifacts arising from novel MR-based attenuation correction (MR-AC) are fully understood. Here we present PET/MR image artifacts following routine MR-AC, as most frequently observed in clinical operations of an integrated whole-body PET/MRI system. A clinical adoption of integrated PET/MRI should entail the joint image display and interpretation of MR data, MR-based attenuation maps and uncorrected plus attenuation-corrected PET images in order to recognize potential pitfalls from MR-AC and to ensure clinically accurate image interpretation.
引用
收藏
页码:173 / 181
页数:9
相关论文
共 25 条
[1]  
Bailey DL, 2005, POSITRON EMISSION TO, V2
[2]   MRI-Based Attenuation Correction for Hybrid PET/MRI Systems: A 4-Class Tissue Segmentation Technique Using a Combined Ultrashort-Echo-Time/Dixon MRI Sequence [J].
Berker, Yannick ;
Franke, Jochen ;
Salomon, Andre ;
Palmowski, Moritz ;
Donker, Henk C. W. ;
Temur, Yavuz ;
Mottaghy, Felix M. ;
Kuhl, Christiane ;
Izquierdo-Garcia, David ;
Fayad, Zahi A. ;
Kiessling, Fabian ;
Schulz, Volkmar .
JOURNAL OF NUCLEAR MEDICINE, 2012, 53 (05) :796-804
[3]  
Beyer T, 2000, J NUCL MED, V41, P1369
[4]  
Beyer T, 2004, J NUCL MED, V45, p25S
[5]  
Beyer T, 2011, INSIGHTS IMAGING, V2, P235, DOI 10.1007/s13244-011-0085-4
[6]  
Czernin J, 2007, J NUCL MED, V48, p78S
[7]  
Delso G, 2011, J NUCL MED, V52, P1914, DOI 10.2967/jnumed.111.092726
[8]   The effect of limited MR field of view in MR/PET attenuation correction [J].
Delso, Gaspar ;
Martinez-Moeller, Axel ;
Bundschuh, Ralph A. ;
Nekolla, Stephan G. ;
Ziegler, Sibylle I. .
MEDICAL PHYSICS, 2010, 37 (06) :2804-2812
[9]   Value of a Dixon-based MR/PET attenuation correction sequence for the localization and evaluation of PET-positive lesions [J].
Eiber, Matthias ;
Martinez-Moeller, Axel ;
Souvatzoglou, Michael ;
Holzapfel, Konstantin ;
Pickhard, Anja ;
Loeffelbein, Dennys ;
Santi, Ivan ;
Rummeny, Ernst J. ;
Ziegler, Sibylle ;
Schwaiger, Markus ;
Nekolla, Stephan G. ;
Beer, Ambros J. .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2011, 38 (09) :1691-1701
[10]   Nonrigid PET motion compensation in the lower abdomen using simultaneous tagged-MRI and PET imaging [J].
Guerin, B. ;
Cho, S. ;
Chun, S. Y. ;
Zhu, X. ;
Alpert, N. M. ;
El Fakhri, G. ;
Reese, T. ;
Catana, C. .
MEDICAL PHYSICS, 2011, 38 (06) :3025-3038