The toxicology of mercury and its compounds

被引:323
作者
Syversen, Tore [1 ]
Kaur, Parvinder [2 ]
机构
[1] Norwegian Univ Sci & Technol, Dept Neurosci, N-7491 Trondheim, Norway
[2] Norwegian Univ Sci & Technol, Dept Dept Circulat & Med Imaging, N-7491 Trondheim, Norway
关键词
Mercury; Methylmercury; Toxicity; Neurotoxicity; METHYLMERCURY-INDUCED NEUROTOXICITY; SEYCHELLES CHILD-DEVELOPMENT; INVIVO PROTEIN-SYNTHESIS; AMINO-ACID TRANSPORTER; METHYL MERCURY; NERVOUS-SYSTEM; RAT-BRAIN; COGNITIVE-DEVELOPMENT; ELEMENTAL MERCURY; INORGANIC MERCURY;
D O I
10.1016/j.jtemb.2012.02.004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A concentrated review on the toxicology of inorganic mercury together with an extensive review on the neurotoxicology of methylmercury is presented. The challenges of using inorganic mercury in dental amalgam are reviewed both regarding the occupational exposure and the possible health problems for the dental patients. The two remaining "mysteries" of methylmercury neurotoxicology are also being reviewed; the cellular selectivity and the delayed onset of symptoms. The relevant literature on these aspects has been discussed and some suggestions towards explaining these observations have been presented. (C) 2012 Elsevier GmbH. All rights reserved.
引用
收藏
页码:215 / 226
页数:12
相关论文
共 168 条
[21]   AUTOMETALLOGRAPHIC DETERMINATION OF INORGANIC MERCURY DISTRIBUTION IN THE CORTEX OF THE CALCARINE SULCUS OF THE MONKEY MACACA-FASCICULARIS FOLLOWING LONG-TERM SUBCLINICAL EXPOSURE TO METHYLMERCURY AND MERCURIC-CHLORIDE [J].
CHARLESTON, JS ;
BODY, RL ;
MOTTET, NK ;
VAHTER, ME ;
BURBACHER, TM .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 1995, 132 (02) :325-333
[22]  
Charleston JS, 1996, NEUROTOXICOLOGY, V17, P127
[23]   INCREASES IN THE NUMBER OF REACTIVE GLIA IN THE VISUAL-CORTEX OF MACACA-FASCICULARIS FOLLOWING SUBCLINICAL LONG-TERM METHYL MERCURY EXPOSURE [J].
CHARLESTON, JS ;
BOLENDER, RP ;
MOTTET, NK ;
BODY, RL ;
VAHTER, ME ;
BURBACHER, TM .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 1994, 129 (02) :196-206
[24]  
CHOI BH, 1980, BRAIN RES, V202, P238, DOI 10.1016/S0006-8993(80)80053-9
[25]   The effects of glutathione glycoside in methyl mercury poisoning [J].
Choi, BH ;
Yee, S ;
Robles, M .
TOXICOLOGY AND APPLIED PHARMACOLOGY, 1996, 141 (02) :357-364
[26]   The toxicology of mercury and its chemical compounds [J].
Clarkson, Thomas W. ;
Magos, Laszlo .
CRITICAL REVIEWS IN TOXICOLOGY, 2006, 36 (08) :609-662
[27]   The three modern faces of mercury [J].
Clarkson, TW .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2002, 110 :11-23
[28]  
CLARKSON TW, 1981, J PHARMACOL EXP THER, V218, P74
[29]   A quantitative analysis of prenatal methyl mercury exposure and cognitive development [J].
Cohen, JT ;
Bellinger, DC ;
Shaywitz, BA .
AMERICAN JOURNAL OF PREVENTIVE MEDICINE, 2005, 29 (04) :353-365
[30]   A quantitative risk-benefit analysis of changes in population fish consumption [J].
Cohen, JT ;
Bellinger, DC ;
Connor, WE ;
Kris-Etherton, PM ;
Lawrence, RS ;
Savitz, DA ;
Shaywitz, BA ;
Teutsch, SM ;
Gray, GM .
AMERICAN JOURNAL OF PREVENTIVE MEDICINE, 2005, 29 (04) :325-334