The toxicology of mercury and its compounds

被引:323
作者
Syversen, Tore [1 ]
Kaur, Parvinder [2 ]
机构
[1] Norwegian Univ Sci & Technol, Dept Neurosci, N-7491 Trondheim, Norway
[2] Norwegian Univ Sci & Technol, Dept Dept Circulat & Med Imaging, N-7491 Trondheim, Norway
关键词
Mercury; Methylmercury; Toxicity; Neurotoxicity; METHYLMERCURY-INDUCED NEUROTOXICITY; SEYCHELLES CHILD-DEVELOPMENT; INVIVO PROTEIN-SYNTHESIS; AMINO-ACID TRANSPORTER; METHYL MERCURY; NERVOUS-SYSTEM; RAT-BRAIN; COGNITIVE-DEVELOPMENT; ELEMENTAL MERCURY; INORGANIC MERCURY;
D O I
10.1016/j.jtemb.2012.02.004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A concentrated review on the toxicology of inorganic mercury together with an extensive review on the neurotoxicology of methylmercury is presented. The challenges of using inorganic mercury in dental amalgam are reviewed both regarding the occupational exposure and the possible health problems for the dental patients. The two remaining "mysteries" of methylmercury neurotoxicology are also being reviewed; the cellular selectivity and the delayed onset of symptoms. The relevant literature on these aspects has been discussed and some suggestions towards explaining these observations have been presented. (C) 2012 Elsevier GmbH. All rights reserved.
引用
收藏
页码:215 / 226
页数:12
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