Protein-templated gold nanoclusters based sensor for off-on detection of ciprofloxacin with a high selectivity

被引：45
作者：
Chen, Zhanguang [1 ]
Qian, Sihua [1 ]
Chen, Junhui [2 ]
Cai, Jie [1 ]
Wu, Shuyan [1 ]
Cai, Ziping [1 ]
机构：
[1] Shantou Univ, Dept Chem, Shantou 515063, Peoples R China
[2] Peking Univ, Shenzhen Hosp, Intervent Oncol & Minimally Invas Therapies Dept, Shenzhen 518036, Peoples R China
来源：
TALANTA | 2012年 / 94卷
关键词：
Gold nanoclusters; Ciprofloxacin; Fluorescence; Quenching; Restoration; LIGHT-SCATTERING TECHNIQUE; SILVER NANOCLUSTERS; LIQUID-CHROMATOGRAPHY; METAL-IONS; FLUORESCENCE; IDENTIFICATION; WATER;
D O I：
10.1016/j.talanta.2012.03.033
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
In this contribution, bovine serum albumin stabilized gold nanoclusters as novel fluorescent probes were successfully utilized for the detection of ciprofloxacin for the first time. Our prepared gold nanoclusters exhibited strong emission with peak maximum at 635 nm. Cu2+ was employed to quench the strong fluorescence of the gold nanoclusters, whereas the addition of ciprofloxacin caused the fluorescence intensity restoration of the Cu2+-gold nanoclusters system. The increase in fluorescence intensity of Cu2+-gold nanoclusters system caused by ciprofloxacin allows the sensitive detection of ciprofloxacin in the range of 0.4 ng mL(-1) to 50 ng mL(-1). The detection limit for ciprofloxacin is 0.3 ng mL(-1) at a signal-to-noise ratio of 3. The present sensor for ciprofloxacin detection possesses a low detection limit and wide linear range. In addition, the real samples were analyzed with satisfactory results. (C) 2012 Elsevier B.V. All rights reserved.
引用
收藏
页码：240 / 245
页数：6
相关论文
共 36 条
[1]   DNA G-quadruplex-templated formation of the fluorescent silver nanocluster and its application to bioimaging [J].
Ai, Jun ;
Guo, Weiwei ;
Li, Bingling ;
Li, Tao ;
Li, Dan ;
Wang, Erkang .
TALANTA, 2012, 88 :450-455
[2]   Preparation of novel composite nanoclusters and their application in the ultrasensitive detection of proteins [J].
Chen, HQ ;
Wang, L ;
Wang, LY ;
Wang, GF ;
Li, L ;
Xu, FG .
ANALYTICA CHIMICA ACTA, 2004, 521 (01) :9-15
[3]   A novel fluorescent array for mercury (II) ion in aqueous solution with functionalized cadmium selenide nanoclusters [J].
Chen, Jinlong ;
Gao, YingChun ;
Xu, ZhiBing ;
Wu, GenHua ;
Chen, YouCun ;
Zhu, ChangQing .
ANALYTICA CHIMICA ACTA, 2006, 577 (01) :77-84
[4]   Use of Gemini surfactant in a one-step ellagic acid assay by resonance light scattering technique [J].
Chen, Zhanguang ;
Peng, Yurui ;
Wang, Shaobin ;
Chen, Xi ;
Song, Tianhe ;
Qian, Sihua ;
Chen, Meizhen ;
Wang, Qinrong .
TALANTA, 2010, 82 (03) :885-891
[5]   Ozonation of ciprofloxacin in water: HRMS identification of reaction products and pathways [J].
Dewitte, Bavo ;
Dewulf, Jo ;
Demeestere, Kristof ;
De Vyvere, Vincent Van ;
De Wispelaere, Patrick ;
Van Langenhove, Herman .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2008, 42 (13) :4889-4895
[6]   Etching colloidal gold nanocrystals with hyperbranched and multivalent polymers: A new route to fluorescent and water-soluble atomic clusters [J].
Duan, Hongwei ;
Nie, Shuming .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (09) :2412-+
[7]   Fluorescent gold clusters as nanosensors for copper ions in live cells [J].
Durgadas, C. V. ;
Sharma, C. P. ;
Sreenivasan, K. .
ANALYST, 2011, 136 (05) :933-940
[8]   Ciprofloxacin and furagin in acute cystitis: comparison of early immune and microbiological results [J].
Dybowski, Bartosz ;
Jablonska, Olga ;
Radziszewski, Piotr ;
Grornadzka-Ostrowska, Joanna ;
Borkowski, Andrzej .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2008, 31 (02) :130-134
[9]   Antibacterial activity of ciprofloxacin-loaded zein microsphere films [J].
Fu, Jian-Xi ;
Wang, Hua-Jie ;
Zhou, Yan-Qing ;
Wang, Jin-Ye .
MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS, 2009, 29 (04) :1161-1166
[10]   Highly Sequence-Dependent Formation of Fluorescent Silver Nanoclusters in Hybridized DNA Duplexes for Single Nucleotide Mutation Identification [J].
Guo, Weiwei ;
Yuan, Jipei ;
Dong, Qingzhe ;
Wang, Erkang .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (03) :932-+
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