FLAVONES FROM CASSIA LESCHENAULTIANA AND THEIR ANTI TOBACCO MOSAIC VIRUS ACTIVITY

被引:0
作者
Kong, Guang-Hui [1 ]
Xing, Huan-Huan [2 ]
Wu, Yu-Ping [1 ]
Xia, Zhen-Yuan [1 ]
Li, Jing [2 ]
Ye, Ling [2 ]
Kong, Wei-Song [2 ]
Liu, Xin [2 ]
Li, Yan-Ping [4 ]
Rao, Gao-Xiong [4 ]
Hu, Qiu-Fen [2 ,5 ]
Yang, Guang-Yu [2 ]
Li, Yin-Ke [1 ,3 ]
Lie, Xue-Mei [2 ]
机构
[1] Yunnan Acad Tobacco Agr Sci, Kunming 650031, Yunnan, Peoples R China
[2] China Tobacco Yunnan Ind Co Ltd, Key Lab Tobacco Chem Yunnan Prov, Kunming 650231, Yunnan, Peoples R China
[3] Yuxi Normal Univ, Coll Resource & Environm, Yuxi 653100, Peoples R China
[4] Yunnan Univ Tradit Chinese Med, Coll Pharmaceut Sci, Kunming 650500, Yunnan, Peoples R China
[5] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, Kunming 650031, Yunnan, Peoples R China
基金
中国国家自然科学基金;
关键词
Cassia leschenaultiana; Flavone; Anti-TMV Activity; FISTULA; SIAMEA; DERIVATIVES; STEMS; BIOACTIVITIES; CYTOTOXICITY; ALKALOIDS; CHROMONES; SEEDS; BARK;
D O I
10.3987/COM-17-13805
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Three new (1-3), together with three known flavones (4-6), were isolated from the whole plants of Cassia leschenaultiana. Their structures were elucidated by spectroscopic methods, including extensive 1D- and 2D NMR techniques. Compounds 1-4 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 3 exhibited high anti-TMV activity with inhibition rate of 48.2%. This inhibition rate is higher than that of positive control (33.8%). Compounds 1, 2, and 4 also showed potential anti-TMV activities with inhibition rates of 29.5%, 26.2%, and 27.8%, respectively.
引用
收藏
页码:2125 / 2131
页数:7
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