Iron-catalyzed unprecedented formation of benzo[d]imidazo[2,1-b]thiazoles under solvent-free conditions

被引：39

作者：

Balwe, Sandip Gangadhar ^{[1
]}

Jeong, Yeon Tae ^{[1
]}

机构：

[1] Pukyong Natl Univ, Dept Image Sci & Engn, Busan 608737, South Korea

来源：

RSC ADVANCES | 2016年 / 6卷 / 109期

关键词：

MULTICOMPONENT REACTIONS; BIOLOGICAL EVALUATION; CYCLIC SULFONAMIDES; NITROALKANES; CYCLIZATION; DISCOVERY; DESIGN; POTENT; PET;

D O I：

10.1039/c6ra24183b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The unprecedented formation of benzo[d]imidazo[2,1-b]thiazole during iron-catalyzed coupling of 2-aminobenzothiazole, aldehydes with nitroalkane in air has been observed. This unique transformation possibly occurs through a sequential aza-Henry reaction and subsequent intramolecular cyclization, followed by denitration. A variety of substituted benzo[d]imidazo[2,1-b]thiazole are obtained using this protocol.

引用

页码：107225 / 107232

页数：8

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