Iron-catalyzed unprecedented formation of benzo[d]imidazo[2,1-b]thiazoles under solvent-free conditions

被引：38
作者：
Balwe, Sandip Gangadhar [1 ]
Jeong, Yeon Tae [1 ]
机构：
[1] Pukyong Natl Univ, Dept Image Sci & Engn, Busan 608737, South Korea
来源：
RSC ADVANCES | 2016年 / 6卷 / 109期
关键词：
MULTICOMPONENT REACTIONS; BIOLOGICAL EVALUATION; CYCLIC SULFONAMIDES; NITROALKANES; CYCLIZATION; DISCOVERY; DESIGN; POTENT; PET;
D O I：
10.1039/c6ra24183b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The unprecedented formation of benzo[d]imidazo[2,1-b]thiazole during iron-catalyzed coupling of 2-aminobenzothiazole, aldehydes with nitroalkane in air has been observed. This unique transformation possibly occurs through a sequential aza-Henry reaction and subsequent intramolecular cyclization, followed by denitration. A variety of substituted benzo[d]imidazo[2,1-b]thiazole are obtained using this protocol.
引用
收藏
页码：107225 / 107232
页数：8
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