Detection by coupled LC-photodiode array detection and high-resolution Orbitrap MS of dimethyl and diethyl yellow dyes used illegally in processed soymilk curd

被引:7
作者
Fang, Mingchih [1 ]
Tsai, Chia-Fen [1 ]
Kuo, Ching-Hao [1 ]
Cheng, Hwei-Fang [1 ]
机构
[1] Taiwan Food & Drug Adm, Taipei, Taiwan
来源
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT | 2015年 / 32卷 / 10期
关键词
dimethyl yellow; diethyl yellow; Orbitrap; high resolution mass spectrometry; tofu; soymilk curd; LIQUID-CHROMATOGRAPHY; MASS-SPECTROMETRY; RED;
D O I
10.1080/19440049.2015.1055830
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
An efficient non-target dye-screening system consisting of a liquid chromatography photodiode array coupled with a high-resolution mass spectrometer (HRMS) is described. Visible absorption spectroscopy assisted in locating the peak of an unknown dye in HRMS chromatograms which allowed the accurate molecular weight of the unknown to be obtained. In a study of the adulteration of processed soymilk curd (tofu) with dimethyl yellow, an unexpected unknown dye was discovered. The compound was further purified by gel permeation chromatography and identified by HRMS and proton nuclear magnetic resonance (NMR) as diethyl yellow (solvent yellow 56). This is the first time that diethyl yellow has been reported in foods. The authentic diethyl yellow was then purchased and used as a quantitative standard. Tofu products and their ingredients associated with tofu processing were surveyed. Analysis showed the source of diethyl yellow could be traced to emulsifiers used as ingredient in tofu products. Surveillance work found the concentrations of diethyl yellow ranged from several g kg(-1) (ppb) in the tofu products to up to hundreds of mg kg(-1) (ppm) in the emulsifiers.
引用
收藏
页码:1730 / 1736
页数:7
相关论文
共 11 条
[1]   N,N-DIETHYL-4-AMINOAZOBENZENE (DEAB) - ACUTE ACTIONS WITH RESPECT TO POSSIBLE CARCINOGENICITY AS WELL AS ROLE OF SOLVENTS - MORPHOLOGICAL AND PHARMACOLOGICAL INVESTIGATIONS [J].
DANZ, M ;
KLINGER, W ;
MULLER, D ;
KLEEBERG, U ;
GLOCKNER, R ;
ZIEBARTH, D ;
URBAN, H .
EXPERIMENTELLE PATHOLOGIE, 1978, 16 (1-6) :245-253
[2]   Determining the adulteration of spices with Sudan I-II-II-IV dyes by UV-visible spectroscopy and multivariate classification techniques [J].
Di Anibal, Carolina V. ;
Odena, Marta ;
Ruisanchez, Itziar ;
Pilar Callao, M. .
TALANTA, 2009, 79 (03) :887-892
[3]  
Gajda Joanna, 2006, Rocz Panstw Zakl Hig, V57, P317
[4]   Determination of Sudan dye residues in eggs by liquid chromatography and gas chromatography-mass spectrometry [J].
He, Limin ;
Su, Yijuan ;
fang, Binghu ;
Shen, Xiangguang ;
Zeng, Zhenling ;
Liu, Yahong .
ANALYTICA CHIMICA ACTA, 2007, 594 (01) :139-146
[5]   Determination of the elemental composition of trace analytes in complex matrices using exact masses of product ions and corresponding neutral losses [J].
Kaufmann, Anton .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2007, 21 (13) :2003-2013
[6]   UPLC-ESI-MS/MS analysis of Sudan dyes and Para Red in food [J].
Li, C. ;
Wu, Y. L. ;
Shen, J. Z. .
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 2010, 27 (09) :1215-1220
[7]   Interference-free simultaneous determination of Sudan dyes in chili foods using solid phase extraction coupled with HPLC-DAD [J].
Qi, Ping ;
Zeng, Tao ;
Wen, Zejun ;
Liang, Xiaoyan ;
Zhang, Xuewu .
FOOD CHEMISTRY, 2011, 125 (04) :1462-1467
[8]   Discovery and structural elucidation of the illegal azo dye Basic Red 46 in sumac spice [J].
Ruf, J. ;
Walter, P. ;
Kandler, H. ;
Kaufmann, A. .
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 2012, 29 (06) :897-907
[9]  
Tanakhan B., 2011, Journal of Agricultural Research and Extension, V28, P46
[10]   Rapid Detection of Dimethyl Yellow Dye in Curry by Liquid Chromatography-Electrospray-Tandem Mass Spectrometry [J].
Tateo, Fernando ;
Bononi, Monica ;
Gallone, Franco .
CZECH JOURNAL OF FOOD SCIENCES, 2010, 28 (05) :427-432