Cloning and expression analysis of a novel tissue-specific dopa decarboxylase mRNA splicing variant in Bombyx mori

被引：6

作者：

Tsukioka, Dai ^{[1
,2
]}

Izumi, Susumu ^{[1
]}

Adachi, Takeshi ^{[1
]}

机构：

[1] Kanagawa Univ, Dept Biol Sci, Fac Sci, Hiratsuka, Kanagawa, Japan

[2] Univ Tokyo, Grad Sch Frontier Sci, Dept Integrated Biosci, Kashiwa, Chiba, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2017年 / 81卷 / 03期

关键词：

dopa decarboxylase; alternative splicing; Bombyx mori; DROSOPHILA; GENE; SILKWORM; DIAPAUSE;

D O I：

10.1080/09168451.2016.1258987

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Dopa decarboxylase (DDC) protein is involved in the synthesis of dopamine and serotonin. Here, we show that in the silkworm Bombyx mori, a novel DDC splicing variant is selectively expressed in the brain and subesophageal ganglia. In Drosophila melanogaster, a neuron-specific isoform of DDC is known to be alternatively spliced in a similar manner.

引用

页码：555 / 557

页数：3

共 10 条

[1] Insect cuticular sclerotization: A review [J].

Andersen, Svend Olav .

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2010, 40 (03) :166-178

[2] cDNA cloning and mRNA expression of L-3,4-dihydroxyphenylalanine decarboxylase gene homologue from the silkworm, Bombyx mori [J].

Hwang, JS ;

Kang, SW ;

Goo, TW ;

Yun, EY ;

Lee, JS ;

Kwon, OY ;

Chun, T ;

Suzuki, Y ;

Fujiwara, H .

BIOTECHNOLOGY LETTERS, 2003, 25 (12) :997-1002

[3] A NEURON-SPECIFIC ENHANCER OF THE DROSOPHILA DOPA DECARBOXYLASE GENE [J].

JOHNSON, WA ;

MCCORMICK, CA ;

BRAY, SJ ;

HIRSH, J .

GENES & DEVELOPMENT, 1989, 3 (05) :676-686

[4] METABOLISM OF TYROSINE-O-PHOSPHATE IN DROSOPHILA [J].

LUNAN, KD ;

MITCHELL, HK .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1969, 132 (02) :450-&

[5] REGULATED SPLICING PRODUCES DIFFERENT FORMS OF DOPA DECARBOXYLASE IN THE CENTRAL-NERVOUS-SYSTEM AND HYPODERM OF DROSOPHILA-MELANOGASTER [J].

MORGAN, BA ;

JOHNSON, WA ;

HIRSH, J .

EMBO JOURNAL, 1986, 5 (12) :3335-3342

[6] Dopamine is a key factor for the induction of egg diapause of the silkworm, Bombyx mori [J].

Noguchi, H ;

Hayakawa, Y .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 2001, 268 (03) :774-780

[7] THE CLONED DOPA DECARBOXYLASE GENE IS DEVELOPMENTALLY REGULATED WHEN REINTEGRATED INTO THE DROSOPHILA GENOME [J].

SCHOLNICK, SB ;

MORGAN, BA ;

HIRSH, J .

CELL, 1983, 34 (01) :37-45

[8] Neuroarchitecture of Aminergic Systems in the Larval Ventral Ganglion of Drosophila melanogaster [J].

Voemel, Matthias ;

Wegener, Christian .

PLOS ONE, 2008, 3 (03)

[9] Phenotypic analysis of the Dopa decarboxylase gene cluster mutants in Drosophila melanogaster [J].

Wright, TRF .

JOURNAL OF HEREDITY, 1996, 87 (03) :175-190

[10] Diapause hormone of the silkworm, Bombyx mori: Structure, gene expression and function [J].

Yamashita, O .

JOURNAL OF INSECT PHYSIOLOGY, 1996, 42 (07) :669-679

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