Sexual Dimorphisms: How Sex-Shared Neurons Generate Sex-Specific Behaviors

被引:2
作者
Banerjee, Navonil [1 ]
Hallem, Elissa [1 ]
机构
[1] Univ Calif Los Angeles, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90095 USA
关键词
CAENORHABDITIS-ELEGANS; DECISION-MAKING; C; ELEGANS; PLASTICITY; PHEROMONES; RESPONSES; CIRCUITS; STATE;
D O I
10.1016/j.cub.2018.01.066
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
How sexually dimorphic behaviors are represented in the brain is a long-standing question. Two new studies in C. elegans uncover novel molecular mechanisms that allow neurons shared by opposite sexes to generate distinct sex-specific behaviors.
引用
收藏
页码:R254 / R256
页数:3
相关论文
共 20 条
[1]   A Single-Neuron Chemosensory Switch Determines the Valence of a Sexually Dimorphic Sensory Behavior [J].
Fagan, Kelli A. ;
Luo, Jintao ;
Lagoy, Ross C. ;
Schroeder, Frank C. ;
Albrecht, Dirk R. ;
Portman, Douglas S. .
CURRENT BIOLOGY, 2018, 28 (06) :902-+
[2]   Neural circuits for sexually dimorphic and sexually divergent behaviors in Caenorhabditis elegans [J].
Garcia, L. Rene ;
Portman, Douglas S. .
CURRENT OPINION IN NEUROBIOLOGY, 2016, 38 :46-52
[3]   Neurexin controls plasticity of a mature, sexually dimorphic neuron [J].
Hart, Michael P. ;
Hobert, Oliver .
NATURE, 2018, 553 (7687) :165-+
[4]   DCC Expression by Neurons Regulates Synaptic Plasticity in the Adult Brain [J].
Horn, Katherine E. ;
Glasgow, Stephen D. ;
Gobert, Delphine ;
Bull, Sarah-Jane ;
Luk, Tamarah ;
Girgis, Jacklyn ;
Tremblay, Marie-Eve ;
McEachern, Danielle ;
Bouchard, Jean-Francois ;
Haber, Michael ;
Hamel, Edith ;
Krimpenfort, Paul ;
Murai, Keith K. ;
Berns, Anton ;
Doucet, Guy ;
Chapman, C. Andrew ;
Ruthazer, Edward S. ;
Kennedy, Timothy E. .
CELL REPORTS, 2013, 3 (01) :173-185
[5]   A Labeled-Line Neural Circuit for Pheromone-Mediated Sexual Behaviors in Mice [J].
Ishii, Kentaro K. ;
Osakada, Takuya ;
Mori, Hiromi ;
Miyasaka, Nobuhiko ;
Yoshihara, Yoshihiro ;
Miyamichi, Kazunari ;
Touhara, Kazushige .
NEURON, 2017, 95 (01) :123-+
[6]   Neuromodulatory State and Sex Specify Alternative Behaviors through Antagonistic Synaptic Pathways in C. elegans [J].
Jang, Heeun ;
Kim, Kyuhyung ;
Neal, Scott J. ;
Macosko, Evan ;
Kim, Dongshin ;
Butcher, Rebecca A. ;
Zeiger, Danna M. ;
Bargmann, Cornelia I. ;
Sengupta, Piali .
NEURON, 2012, 75 (04) :585-592
[7]   The Connectome of a Decision-Making Neural Network [J].
Jarrell, Travis A. ;
Wang, Yi ;
Bloniarz, Adam E. ;
Brittin, Christopher A. ;
Xu, Meng ;
Thomson, J. Nichol ;
Albertson, Donna G. ;
Hall, David H. ;
Emmons, Scott W. .
SCIENCE, 2012, 337 (6093) :437-444
[8]   Pheromone processing in Drosophila [J].
Kohl, Johannes ;
Huoviala, Paavo ;
Jefferis, Gregory S. X. E. .
CURRENT OPINION IN NEUROBIOLOGY, 2015, 34 :149-157
[9]   Mating pheromones of Nematoda: olfactory signaling with physiological consequences [J].
Leighton, Daniel H. W. ;
Sternberg, Paul W. .
CURRENT OPINION IN NEUROBIOLOGY, 2016, 38 :119-124
[10]   Contrasting responses within a single neuron class enable sex-specific attraction in Caenorhabditis elegans [J].
Narayan, Anusha ;
Venkatachalam, Vivek ;
Durak, Omer ;
Reilly, Douglas K. ;
Bose, Neelanjan ;
Schroeder, Frank C. ;
Samuel, Aravinthan D. T. ;
Srinivasan, Jagan ;
Sternberg, Paul W. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016, 113 (10) :E1392-E1401