Emerging Implantable Energy Harvesters and Self-Powered Implantable Medical Electronics

被引:274
作者
Jiang, Dongjie [1 ,2 ]
Shi, Bojing [4 ]
Ouyang, Han [4 ]
Fan, Yubo [4 ]
Wang, Zhong Lin [1 ,2 ,3 ,5 ]
Li, Zhou [1 ,2 ,3 ]
机构
[1] Chinese Acad Sci, CAS Ctr Excellence Nanosci, Beijing Key Lab Micronano Energy & Sensor, Beijing Inst Nanoenergy & Nanosyst, Beijing 100083, Peoples R China
[2] Univ Chinese Acad Sci, Sch Nanosci & Technol, Beijing 100049, Peoples R China
[3] Guangxi Univ, Ctr Nanoenergy Res, Sch Phys Sci & Technol, Nanning 530004, Peoples R China
[4] Beihang Univ, Beijing Adv Innovat Ctr Biomed Engn, Key Lab Biomech & Mechanobiol, Minist Educ,Sch Biol Sci & Med Engn, Beijing 100083, Peoples R China
[5] Georgia Inst Technol, Sch Mat Sci & Engn, Atlanta, GA 30332 USA
基金
中国博士后科学基金; 北京市自然科学基金; 中国国家自然科学基金;
关键词
implantable; energy harvesting; self-powered; medical devices; long-term; pacemaker; nerve stimulation; physiological sensor; biodegradable; bioelectronics; BIOFUEL CELL; TRIBOELECTRIC NANOGENERATOR; ELECTRICAL-STIMULATION; PACEMAKER; SYSTEM; BATTERYLESS; MICROSYSTEMS; GENERATION; HEART; BODY;
D O I
10.1021/acsnano.9b08268
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Implantable energy harvesters (IEHs) are the crucial component for self-powered devices. By harvesting energy from organisms such as heartbeat, respiration, and chemical energy from the redox reaction of glucose, IEHs are utilized as the power source of implantable medical electronics. In this review, we summarize the IEHs and self-powered implantable medical electronics (SIMEs). The typical IEHs are nanogenerators, biofuel cells, electromagnetic generators, and transcutaneous energy harvesting devices that are based on ultrasonic or optical energy. A benefit from these technologies of energy harvesting in vivo, SIMEs emerged, including cardiac pacemakers, nerve/muscle stimulators, and physiological sensors. We provide perspectives on the challenges and potential solutions associated with IEHs and SIMEs. Beyond the energy issue, we highlight the implanted devices that show the therapeutic function in vivo.
引用
收藏
页码:6436 / 6448
页数:13
相关论文
共 97 条
[1]   Development of a battery-free ultrasonically powered functional electrical stimulator for movement restoration after paralyzing spinal cord injury [J].
Alam, Monzurul ;
Li, Shuai ;
Ahmed, Rakib Uddin ;
Yam, Yat Man ;
Thakur, Suman ;
Wang, Xiao-Yun ;
Tang, Dan ;
Ng, Serena ;
Zheng, Yong-Ping .
JOURNAL OF NEUROENGINEERING AND REHABILITATION, 2019, 16 (1)
[2]   A review of acoustic power transfer for biomedical implants [J].
Basaeri, Hamid ;
Christensen, David B. ;
Roundy, Shad .
SMART MATERIALS AND STRUCTURES, 2016, 25 (12)
[3]   A Microelectronic Sensor Device Powered by a Small Implantable Biofuel Cell [J].
Bollella, Paolo ;
Lee, Inhee ;
Blaauw, David ;
Katz, Evgeny .
CHEMPHYSCHEM, 2020, 21 (01) :120-128
[4]   Biofuel Cell Operating in Vivo in Rat [J].
Castorena-Gonzalez, Jorge A. ;
Foote, Christopher ;
MacVittie, Kevin ;
Halamek, Jan ;
Halamkova, Lenka ;
Martinez-Lemus, Luis A. ;
Katz, Evgeny .
ELECTROANALYSIS, 2013, 25 (07) :1579-1584
[5]   Implantable and self-powered blood pressure monitoring based on a piezoelectric thinfilm: Simulated, in vitro and in vivo studies [J].
Cheng, Xiaoliang ;
Xue, Xiang ;
Ma, Ye ;
Han, Mengdi ;
Zhang, Wei ;
Xu, Zhiyun ;
Zhang, Hao ;
Zhang, Haixia .
NANO ENERGY, 2016, 22 :453-460
[6]   A Glucose BioFuel Cell Implanted in Rats [J].
Cinquin, Philippe ;
Gondran, Chantal ;
Giroud, Fabien ;
Mazabrard, Simon ;
Pellissier, Aymeric ;
Boucher, Francois ;
Alcaraz, Jean-Pierre ;
Gorgy, Karine ;
Lenouvel, Francois ;
Mathe, Stephane ;
Porcu, Paolo ;
Cosnier, Serge .
PLOS ONE, 2010, 5 (05)
[7]   Towards glucose biofuel cells implanted in human body for powering artificial organs: Review [J].
Cosnier, Serge ;
Le Goff, Alan ;
Holzinger, Michael .
ELECTROCHEMISTRY COMMUNICATIONS, 2014, 38 :19-23
[8]   Biodegradable Piezoelectric Force Sensor [J].
Curry, Eli J. ;
Ke, Kai ;
Chorsi, Meysam T. ;
Wrobel, Kinga S. ;
Miller, Albert N., III ;
Patel, Avi ;
Kim, Insoo ;
Feng, Jianlin ;
Yue, Lixia ;
Wu, Qian ;
Kuo, Chia-Ling ;
Lo, Kevin W. -H. ;
Laurencin, Cato T. ;
Ilies, Horea ;
Purohit, Prashant K. ;
Nguyen, Thanh D. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (05) :909-914
[9]   Energy Harvesting from the Animal/Human Body for Self-Powered Electronics [J].
Dagdeviren, Canan ;
Li, Zhou ;
Wang, Zhong Lin .
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 19, 2017, 19 :85-108
[10]   Conformal piezoelectric energy harvesting and storage from motions of the heart, lung, and diaphragm [J].
Dagdeviren, Canan ;
Yang, Byung Duk ;
Su, Yewang ;
Tran, Phat L. ;
Joe, Pauline ;
Anderson, Eric ;
Xia, Jing ;
Doraiswamy, Vijay ;
Dehdashti, Behrooz ;
Feng, Xue ;
Lu, Bingwei ;
Poston, Robert ;
Khalpey, Zain ;
Ghaffari, Roozbeh ;
Huang, Yonggang ;
Slepian, Marvin J. ;
Rogers, John A. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (05) :1927-1932