Rapid and Extensive Expansion in the United States of a New Multidrug-resistant Escherichia coli Clonal Group, Sequence Type 1193

被引:80
作者
Tchesnokova, Veronika L. [1 ]
Rechkina, Elena [2 ]
Larson, Lydia [1 ]
Ferrier, Kendra [1 ]
Weaver, Jamie Lee [1 ]
Schroeder, David W. [1 ]
She, Rosemary [3 ]
Butler-Wu, Susan M. [3 ]
Aguero-Rosenfeld, Maria E. [4 ]
Zerr, Danielle [5 ]
Fang, Ferric C. [1 ,6 ]
Ralston, James [7 ,8 ]
Riddell, Kim [7 ]
Scholes, Delia [7 ,8 ]
Weissman, Scott [5 ]
Parker, Kaveri [2 ]
Spellberg, Brad [3 ]
Johnson, James R. [9 ,10 ]
Sokurenko, Evgeni V. [1 ]
机构
[1] Univ Washington, Sch Med, Dept Microbiol, Box 357735, Seattle, WA 98195 USA
[2] ID Genom Inc, Seattle, WA USA
[3] Univ Southern Calif, Keck Sch Med, Los Angeles, CA 90033 USA
[4] NYU, Langone Hosp, New York, NY USA
[5] Seattle Childrens Hosp, Seattle, WA USA
[6] Univ Washington, Harborview Med Ctr, Sch Med, Seattle, WA 98104 USA
[7] Kaiser Permanente Washington, Seattle, WA USA
[8] Kaiser Permanente Washington, Res Inst, Seattle, WA USA
[9] Vet Affairs Med Ctr, Minneapolis, MN USA
[10] Univ Minnesota, Minneapolis, MN USA
基金
美国国家卫生研究院;
关键词
urinary tract infections; Escherichia coli; fluoroquinolone resistance; INFECTIONS; PREVALENCE; ST1193;
D O I
10.1093/cid/ciy525
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We describe the rapid and ongoing emergence across multiple US cities of a new multidrug-resistant Escherichia coli clone-sequence type (ST) 1193-resistant to fluoroquinolones (100%), trimethoprim-sulfamethoxazole (55%), and tetracycline (53%). ST1193 is associated with younger adults (age <40 years) and currently comprises a quarter of fluoroquinolone-resistant clinical E. coli urine isolates.
引用
收藏
页码:334 / 337
页数:4
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