Narrowly Dispersed Hydrophilic Molecularly Imprinted Polymer Nanoparticles for Efficient Molecular Recognition in Real Aqueous Samples Including River Water, Milk, and Bovine Serum

被引：204

作者：

Ma, Yue ^{[1
]}

Pan, Guoqing ^{[1
]}

Zhang, Ying ^{[1
]}

Guo, Xianzhi ^{[1
]}

Zhang, Huiqi ^{[1
]}

机构：

[1] Nankai Univ, Dept Chem, Key Lab Funct Polymer Mat, Minist Educ, Tianjin 300071, Peoples R China

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 05期

基金：

中国国家自然科学基金;

关键词：

biological samples; molecular recognition; polymers; precipitation polymerization; synthetic receptors; RAFT PRECIPITATION POLYMERIZATION; TRANSFER RADICAL POLYMERIZATION; CHAIN TRANSFER POLYMERIZATION; SORBENT ASSAYS; SELECTIVE RECOGNITION; PROTEIN RECOGNITION; ENZYME-INHIBITORS; RECEPTORS; MICROSPHERES; ANTIBODIES;

D O I：

10.1002/anie.201206514

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In river water, milk, and bovine serum, molecularly imprinted polymer nanoparticles with hydrophilic polymer brushes showed excellent molecular recognition (see picture). Readily prepared by precipitation polymerization with a macromolecular chain-transfer agent, such nanoparticles are promising alternatives to antibodies for many applications owing to their superior dispersion and binding properties in biological matrices. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：1511 / 1514

页数：4

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