Development of CMC hydrogels loaded with silver nano-particles for medical applications

被引：255

作者：

Hebeish, Ali ^{[1
]}

Hashem, M. ^{[1
]}

Abd El-Hady, M. M. ^{[1
]}

Sharaf, S. ^{[1
]}

机构：

[1] Natl Res Ctr, Text Res Div, Cairo, Egypt

来源：

CARBOHYDRATE POLYMERS | 2013年 / 92卷 / 01期

关键词：

Carboxymethyl cellulose (CMC); Hydrogels; Silver nanoparticles; Swelling behavior; SUPERABSORBENT HYDROGEL; NANOCOMPOSITES; POLYMER; NANOPARTICLES; POLYSACCHARIDE; CELLULOSE; BEHAVIOR; REMOVAL; ACID;

D O I：

10.1016/j.carbpol.2012.08.094

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Innovative CMC-based hydrogels with great potentials for usage in medical area were principally synthesized as per two strategies. The first involved reaction of epichlorohydrin in alkaline medium containing silver nitrate to yield silver nano-particles (AgNPs)-loaded CMC hydrogel. While CMC acted as stabilizing for AgNPs, trisodium citrate was added to the reaction medium to assist CMC in establishing reduction of Ag. to AgNPs. The second strategy entailed preparation of CMC hydrogel which assists the in situ preparation of AgNPs under the same conditions. In both strategies, factors affecting the characterization of AgNPs-loaded CMC hydrogels were studied. Analysis and characterization of the so obtained hydrogels were performed through monitoring swelling behavior. FTIR spectroscopy, SEM, EDX, UV-vis spectrophotometer and TEM. Antimicrobial activity of the hydrogels was examined and mechanisms involved in their synthesis were reported. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：407 / 413

页数：7

共 30 条

[1] Use of rice straw and radiation-modified maize starch/acrylonitrile in the treatment of wastewater [J].